IdentifierDBSNPE007261
DrugDB01418 (Acenocoumarol)
Interacting Gene/EnzymeCytochrome P450 2C9
Gene NameCYP2C9
UniProt IDP11712
Defining Change(s)
1465C>Trs9332239
Allele NameCYP2C9*12
Genotype(s)Not Available
Type(s)Effect Inferred
GroupsDecreased CYP2C9
DescriptionPoor drug metabolizer, associated with lower dose requirement.
References
  1. Blaisdell J, Jorge-Nebert LF, Coulter S, Ferguson SS, Lee SJ, Chanas B, Xi T, Mohrenweiser H, Ghanayem B, Goldstein JA: Discovery of new potentially defective alleles of human CYP2C9. Pharmacogenetics. 2004 Aug;14(8):527-37. [PubMed:15284535 ]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]