IdentifierDBSNPE007269
DrugDB01418 (Acenocoumarol)
Interacting Gene/EnzymeCytochrome P450 2C9
Gene NameCYP2C9
UniProt IDP11712
Defining Change(s)
395G>Ars200183364
Allele NameCYP2C9*33
Genotype(s)Not Available
Type(s)Effect Inferred
GroupsDecreased CYP2C9
DescriptionPoor drug metabolizer, associated with lower dose requirement.
References
  1. Yin T, Maekawa K, Kamide K, Saito Y, Hanada H, Miyashita K, Kokubo Y, Akaiwa Y, Otsubo R, Nagatsuka K, Otsuki T, Horio T, Takiuchi S, Kawano Y, Minematsu K, Naritomi H, Tomoike H, Sawada J, Miyata T: Genetic variations of CYP2C9 in 724 Japanese individuals and their impact on the antihypertensive effects of losartan. Hypertens Res. 2008 Aug;31(8):1549-57. doi: 10.1291/hypres.31.1549. [PubMed:18971529 ]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]