Mrv1909 03102001362D 62 70 0 0 0 0 999 V2000 2.3274 -0.5318 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 2.3063 -1.9607 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 1.9003 -1.2472 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 1.0758 -1.2392 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5523 -1.2518 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 3.1463 -0.5383 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 0.6783 -0.5158 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1274 -1.9709 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 1.0983 0.1955 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1581 0.8870 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1306 -0.5422 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6643 0.9068 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5698 0.1751 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6488 -3.0465 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5552 0.1700 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9243 0.1931 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6536 -1.9470 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5299 -2.6864 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3697 -1.2640 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1880 -3.2686 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1023 0.8859 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7089 -2.6764 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7918 -0.5562 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8948 -3.0829 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.1751 -1.9317 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5128 -3.2590 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9511 -1.9696 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3942 0.1671 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0649 -3.7685 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4062 0.1815 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5194 -3.8568 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8994 -0.6509 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6515 -4.4177 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7771 -1.9717 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4762 -1.9512 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7374 0.1881 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2237 2.6593 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 -1.9420 3.0718 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9420 3.8968 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6503 2.6594 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.3669 3.9010 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3669 3.0760 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1245 4.4177 0.0000 N 0 0 1 0 0 0 0 0 0 0 0 0 -0.5045 3.0718 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2295 4.3134 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2994 3.5052 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 0.1453 2.5636 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 0.9327 4.2426 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5369 3.5385 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5128 3.9010 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9495 2.7635 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1910 4.0469 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.0836 4.3094 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0752 2.6552 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8828 2.9261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7077 2.9302 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7918 3.8927 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7918 3.0677 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8172 1.6386 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6379 1.6426 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4088 0.9302 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.0503 0.9344 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 19 5 1 0 0 0 0 20 18 1 0 0 0 0 21 16 1 0 0 0 0 2 22 1 1 0 0 0 23 28 1 0 0 0 0 24 14 2 0 0 0 0 25 17 2 0 0 0 0 26 20 2 0 0 0 0 5 27 1 6 0 0 0 28 13 1 0 0 0 0 29 14 1 0 0 0 0 30 15 1 0 0 0 0 31 20 1 0 0 0 0 32 30 1 0 0 0 0 33 29 1 0 0 0 0 34 27 1 0 0 0 0 3 35 1 1 0 0 0 6 36 1 6 0 0 0 7 9 2 0 0 0 0 3 4 1 0 0 0 0 37 10 1 6 0 0 0 21 13 1 0 0 0 0 8 2 1 0 0 0 0 23 19 2 0 0 0 0 1 9 1 6 0 0 0 2 3 1 0 0 0 0 3 1 1 0 0 0 0 4 7 1 0 0 0 0 5 6 1 0 0 0 0 6 1 1 0 0 0 0 7 11 1 0 0 0 0 8 5 1 0 0 0 0 9 12 1 0 0 0 0 11 15 2 0 0 0 0 12 10 2 0 0 0 0 13 6 1 0 0 0 0 2 14 1 6 0 0 0 38 37 1 0 0 0 0 39 38 2 0 0 0 0 40 38 1 0 0 0 0 41 39 1 0 0 0 0 42 40 1 0 0 0 0 43 49 1 6 0 0 0 44 37 1 0 0 0 0 45 39 1 0 0 0 0 46 51 1 0 0 0 0 47 44 1 0 0 0 0 48 46 1 0 0 0 0 47 49 1 6 0 0 0 50 45 1 0 0 0 0 51 47 1 0 0 0 0 46 52 1 1 0 0 0 53 41 2 0 0 0 0 54 42 2 0 0 0 0 46 55 1 6 0 0 0 56 55 1 0 0 0 0 57 53 1 0 0 0 0 58 54 1 0 0 0 0 42 41 1 0 0 0 0 43 50 1 0 0 0 0 48 43 1 0 0 0 0 58 57 2 0 0 0 0 15 10 1 0 0 0 0 37 59 1 1 0 0 0 16 1 1 0 0 0 0 59 60 1 0 0 0 0 17 4 1 0 0 0 0 59 61 2 0 0 0 0 8 18 1 1 0 0 0 60 62 1 0 0 0 0 M END > DB00541 > drugbank > [H][C@@]12N3CC[C@@]11C4=C(C=C(OC)C(=C4)[C@]4(C[C@H]5C[N@](C[C@](O)(CC)C5)CCC5=C4NC4=CC=CC=C54)C(=O)OC)N(C=O)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC > InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37-,38+,39+,42-,43+,44+,45-,46-/m0/s1 > OGWKCGZFUXNPDA-CFWMRBGOSA-N > C46H56N4O10 > 824.972 > 824.399644019 > 9 > 116 > 1.8919715794769467 > 88.31836267192512 > 1 > 3 > 0 > 0 > methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(1R,13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraene-10-carboxylate > 3.36 > 3.128179157333334 > -4.44 > 1 > 2 > 9 > 2 > 14.40514178005572 > 10.849017536198744 > 8.662524172947247 > 171.17 > 221.48039999999995 > 10 > 0 > 3.00e-02 g/l > ENTA > 0 > DB00541 > APRD00495 > approved; investigational > Vincristine > 22-Oxovincaleukoblastin; 22-Oxovincaleukoblastine; Leurocristine; Vincristin; Vincristina; Vincristine; Vincristinum > Marqibo; Oncovin Solution 1mg/ml; VinCRIStine Sulfate; Vincasar PFS; Vincristine Sulfate Inj 1mg/ml USP; Vincristine Sulfate Inj 5mg/vial USP; Vincristine Sulfate Injection; Vincristine Sulfate Injection USP > Alcavixin; Alcrist; Citomid; Cytocristin; Oncocristin; Oncovin; Oncrivin; Sindovin; Tevacristin; Vinces; Vincrisin; Vincristin; Vincrisul; Vinlon; Vinracine > Vincristine sulfate $$$$