Mrv0541 06161316122D          
 
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M  END
> <DATABASE_ID>
DB00588

> <DATABASE_NAME>
drugbank

> <SMILES>
[H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C

> <INCHI_IDENTIFIER>
InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1

> <INCHI_KEY>
WMWTYOKRWGGJOA-CENSZEJFSA-N

> <FORMULA>
C25H31F3O5S

> <MOLECULAR_WEIGHT>
500.571

> <EXACT_MASS>
500.184429407

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
65

> <JCHEM_AVERAGE_NEUTRAL_MICROSPECIES_CHARGE>
-2.6327301250774323e-07

> <JCHEM_AVERAGE_POLARIZABILITY>
49.28997299145852

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
1

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(1R,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1-{[(fluoromethyl)sulfanyl]carbonyl}-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate

> <ALOGPS_LOGP>
3.69

> <JCHEM_LOGP>
3.718004615666666

> <ALOGPS_LOGS>
-4.64

> <JCHEM_MDDR_LIKE_RULE>
1

> <JCHEM_NEUTRAL_CHARGE>
0

> <JCHEM_NUMBER_OF_RINGS>
4

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA>
14.80471291498652

> <JCHEM_PKA_STRONGEST_ACIDIC>
13.606186903754944

> <JCHEM_PKA_STRONGEST_BASIC>
-3.393545718097036

> <JCHEM_POLAR_SURFACE_AREA>
80.67

> <JCHEM_REFRACTIVITY>
121.65029999999997

> <JCHEM_ROTATABLE_BOND_COUNT>
6

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
1.14e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
biotin

> <JCHEM_VEBER_RULE>
0

> <DRUGBANK_ID>
DB00588

> <SECONDARY_ACCESSION_NUMBERS>
APRD00065

> <DRUG_GROUPS>
approved

> <GENERIC_NAME>
Fluticasone propionate

> <SYNONYMS>
Fluticasone propionate

> <PRODUCTS>
24 Hour Allergy Nasal; 24 Hour Allergy Relief Nasal; 24 Hour Allergy Relief nasal; 24hr Nasal Allergy Relief; Advair 100 Diskus; Advair 125; Advair 250; Advair 250 Diskus; Advair 500 Diskus; Advair Diskus; Advair HFA; Advairdiskus Diskus; Aermony Respiclick; AirDuo Digihaler; AirDuo RespiClick; Airexar Spiromax; Allergy Nasal; Allergy Relief; Allergy Relief Nasal; Allergy Relief Nasal Spray; Apo-azelastine/fluticasone; Apo-fluticasone; Apo-fluticasone HFA; Arbesda Respiclick; ArmonAir Digihaler; ArmonAir RespiClick; Azelastine Hydrochloride and Fluticasone Propionate; Azelastine hydrochloride and Fluticasone propionate; Basic Care Allergy Relief Nasal; Basic Care Childrens Allergy Relief Nasal; Berkley and Jensen Allergy Relief; Beser; Betr Allergy Relief Nasal; Bropair Spiromax; CareOne Allergy Relief; Careone Childrens Allergy Relief; Careone Fluticasone Propionate; Caring Mill Allergy Relief Nasal; Caring Mill Childrens Allergy Relief Nasal; Cenovia; Childrens 24 Hour Allergy Relief Nasal; Childrens 24 hour allergy nasal; Childrens Allergy Nasal; Childrens Flonase Allergy Relief; Childrens Nasal; Childrens Nasopro; ClariSpray Nasal Allergy; Core Values Allergy Relief; Cutivate; DG Health Allergy Relief; DG Health Allergy Relief Nasal; DG Health childrens allergy relief nasal; Dymista; Equaline Fluticasone Propionate; Equaline fluticasone propionate; Equate Allergy Relief; Exchange Select Allergy Relief; Family Wellness Allergy Relief Nasal; Flonase; Flonase - Aem-sus Nas 50mcg/md; Flonase Aem-sus 50mcg/aem; Flonase Allergy Relief; Flonaseallergy Relief Allergy Relief; Flovent; Flovent Diskus; Flovent HFA; Flovent Inhalers - Aem Inh-orl 125mcg/aem; Flovent Inhalers - Aem Inh-orl 250mcg/aem; Flovent Inhalers - Aem Inh-orl 25mcg/aem; Flovent Inhalers - Aem Inh-orl 50mcg/aem; Flovent Inhalers-aem Inh-orl 25mcg/actuation; Flovent Inhalers-aem Inh-orl 50mcg/actuation; Flovent Inhalers-aem Inh-orl125mcg/actuation; Flovent Inhalers-aem Inh-orl250mcg/actuation; FlutiCare Nasal Alergy; FlutiCare Nasal Allergy; Fluticasone; Fluticasone Propionate; Fluticasone Propionate 0.05% / Niacinamide 4%; Fluticasone Propionate Diskus; Fluticasone Propionate HFA; Fluticasone Propionate Nasal; Fluticasone Propionate and Salmeterol; Fluticasone Propionate and Salmeterol DISKUS; Fluticasone Propionate and Salmeterol HFA; Fluticasone Propionate spray, metered; Fluticasone propionate; Fluticasone propionate glucocorticoid; Foster and Thrive Allergy Relief; Good Neighbor Pharmacy Childrens Fluticasone Propionate; Good Neighbor Pharmacy Fluticasone Propionate; Good Sense 24 hour allergy nasal; Good Sense Nasoflow; Harris Teeter Allergy Relief Nasal; Health Mart Allergy Relief Nasal 24 Hr; Healthy Accents Allergy Relief; Healthy Accents Nasoflow; Kirkland Signature Aller Flo; Leader Allergy Relief Nasal; Mylan-azelastine/fluticasone; Nasal; Nasoflow; Nasopro 24; Nu-fluticasone; PMS-fluticasone; PMS-fluticasone HFA; PMS-fluticasone Propionate/salmeterol Dpi; Picnic Allergy Symptom Reliever Nasal; Ratio-fluticasone; Rugby Fluticasone Propionate Nasal; Seffalair Spiromax; ShopRite Allergy Relief Nasal; Signature Care Allergy Relief; Signature Care Childrens Allergy Relief; Smart Sense Allergy Relief; Sound Body Allergy Relief; SunMark allergy relief nasal 24 hr; Teva-fluticasone; Ticalast; Ticanase; Ticaspray; TopCare Childrens Allergy Relief Nasal 24 Hour; TopCare Nasoflow Allergy Relief; Topcare Fluticasone Propionate Nasal; Up and Up Allergy Relief Nasal; Up and Up allergy relief nasal; Validerm; Welby Allergy Relief; Welby Fluticasone; Wixela Inhub; Xhance

> <INTERNATIONAL_BRANDS>
Ezicas; Flixonase; Flixotide; FLOVENTHFA; Flunase; Nasofan; Pirinase; Seretide

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