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Displaying drugs 26 - 50 of 5297 in total
Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors. Zolpidem is used for the short-term treatment of insomnia. It works quickly (usually within 15 minutes) and has a short half-life (2-3...
Approved
Matched Synonyms: … N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide …
Matched Iupac: … N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide …
Matched Description: … It works quickly (usually within 15 minutes) and has a short half-life (2-3 hours). ... Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric …
Matched Categories: … GABA-A Receptor Agonists …
Influenza a virus a/california/7/2009 (h1n1) live (attenuated) antigen is a vaccine.
Approved
Matched Synonyms: … Influenza a Virus A/california/7/2009 (H1n1) Live(attenuated) Antigen ... Influenza a virus a/california/7/2009(h1n1) live(attenuated) antigen …
Matched Name: … Influenza a virus a/california/7/2009 (h1n1) live (attenuated) antigen …
Matched Description: … Influenza a virus a/california/7/2009 (h1n1) live (attenuated) antigen is a vaccine. …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Matched Products: … Influenza A H1N1 2009 Monovalent Vaccine Live Intranasal …
Purified botulinum toxin from Clostridium botulinum, purified from culture via dialysis and acid precipitation.
Approved
Investigational
Matched Synonyms: … BTX-A ... Botulinum toxin A ... Botulinum A neurotoxin …
Matched Name: … Botulinum toxin type A
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
A tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant staphylococcus infections.
Approved
Investigational
Matched Synonyms: … (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … A tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is …
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic...
Approved
Vet approved
Matched Synonyms: … Bacitracin A
Matched Description: … knee scrape from a girl named Margaret Tracy. ... As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. ... Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group …
Gadoteridol provides contrast enhancement of the brain, spine and surrounding tissues resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to cause a disruption of the normal blood brain barrier. Gadoteridol can also be used for whole body contrast enhanced MRI including the...
Approved
Investigational
Matched Synonyms: … Gd-HPDO3A ... GD-HP-DO 3A ... gadolinium-HP-DO3A
Matched Description: … visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to cause a ... When placed in a magnetic field, gadoteridol shortens the T1 relaxation time in tissues where it accumulates …
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a US National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol....
Approved
Vet approved
Matched Synonyms: … Taxol A ... 3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca ... 12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a, …
Matched Description: … Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. ... It was discovered in a US National Cancer Institute program at the Research Triangle Institute in 1967 ... In this formulation, paclitaxel is dissolved in Kolliphor EL and ethanol, as a delivery agent. …
Matched Categories: … Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord. It is structurally...
Approved
Matched Synonyms: … (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine ... N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine ... N,N-Dimethyl-5H-dibenzo(a,D)cycloheptene-delta(5,gamma)-propylamine …
Matched Description: … Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis. Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown...
Approved
Investigational
Matched Synonyms: … (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin …
Matched Description: … Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the ... hydrochloride salt form and is marketed as oral tablets under the brand name Norprolac contained as a
Teicoplanin is a glycopeptide antibiotic. It is a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, termed teicoplanin A3-1, a fused ring structure to which two carbohydrates (mannose and N-acetylglucosamine) are attached....
Approved
Investigational
Matched Synonyms: … Teichomycin A2 …
Matched Description: … Teicoplanin is a glycopeptide antibiotic. ... All teicoplanins share a same glycopeptide core, termed teicoplanin A3-1, a fused ring structure to which ... only by the length and conformation of a side chain attached to it. …
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.
Approved
Investigational
Matched Synonyms: … anti-CD11a
Matched Description: … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ... ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. …
A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Synonyms: … 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Matched Description: … A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various ... It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease …
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … Chymotrypsin A
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins …
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Synonyms: … A F Green No.2 ... Acid Green A ... A.F. Green No. 2 …
Matched Description: … solution which is widely used as a counterstain. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining ... It is used in histological applications and other labratory settings, and usually exists as a disodium …
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … -3-yl]-1H-benzimidazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1- ... 9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[2.2.1]hept
Matched Description: … Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627]. ... Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … DTP-A
Matched Description: … Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic ... [A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive …
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Synonyms: … 6-O-methylerythromycin A
Matched Description: … Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein …
Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with [DB13878], glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Synonyms: … difluoromethyl)-1-[(1-methylcyclopropane-1-sulfonyl)carbamoyl]cyclopropyl}-20,20-difluoro­ 5,8-dioxo-2,3,3a, ... 5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12­ methanocyclopenta[18,19][1,10,17,3,6]trioxadiazacyclononadecino …
Matched Description: … It demonstrates a high genetic barrier against resistance mutations of the virus. ... Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor ... In combination with [DB13878], glecaprevir is a useful therapy for patients who experienced therapeutic …
Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup Y. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.
Approved
Experimental
Investigational
Matched Synonyms: … Neisseria meningitidis group Y polysaccharide antigen, A
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia …
Matched Mixtures name: … Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 …
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2- …
Matched Iupac: … (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic …
Matched Description: … A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. …
A lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses,...
Approved
Matched Synonyms: … 9-HYDROXY-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-D][1,3]dioxol-6(5ah …
Matched Description: … It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... A lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. …
Approved
Experimental
Matched Synonyms: … Protein-type A microspheres …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of...
Approved
Matched Synonyms: … 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy …
Matched Description: … It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl ... Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce ... Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. …
Displaying drugs 26 - 50 of 5297 in total