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Lovastatin is a cholesterol-lowering agent that belongs to the class of medications called statins. It was the second agent of this class discovered. It was discovered by Alfred Alberts and his team at Merck in 1978 after screening only 18 compounds over 2 weeks. The agent, also known as mevinolin,...
Approved
Investigational
Matched Synonyms: … (1S,3R,7S,8S,8AR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-py …
Matched Description: … hydroxymethylglutarate (HMG), a substituent of HMG-Coenzyme A (HMG-CoA), a substrate of the cholesterol ... mevastatin by a single methyl group at the 6’ position. Lovastatin is a prodrug that is activated by in vivo ... acid pathway. Lovastatin is a competitive inhibitor of HMG-CoA reductase with a binding affinity 20,000 times …
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … FSH-a
Matched Description: … which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF) ... injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility ... indistinguishable. However, a more recent study showed there is may be a slight clinical difference, …
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and ... Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride …
Matched Products: … Hetastarch In Sodium Chloride …
Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the...
Approved
Nutraceutical
Matched Description: … Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension ... and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension ... the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. …
Matched Mixtures name: … Port A Mins Super Cal-mag 300/150 With Vitamin D3 ... Port A Mins Super Cal-mag 600/300 ... One A Day Tab …
Matched Products: … Port A Mins Super Magnesium 188 ... Port A Mins Super Magnesium 375 …
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Approved
Investigational
Matched Description: … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia ... dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase …
Matched Products: … Rivastigmine 1 A Pharma …
Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved...
Approved
Matched Description: … used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal ... Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and ... are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment …
Matched Products: … Orajel Naturals FAst Relief for Teething Pain …
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white color of the pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly...
Approved
Matched Description: … often displays a yellow color compared to the white color of the pure compound. It is used in various chemical ... Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron ... chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used …
Matched Categories: … Anti-Acne Preparations for Topical Use …
Matched Products: … Hemox A
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals. [PubChem]
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid …
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. It is a chelating ... chelating agent for heavy metals. [PubChem] …
Matched Mixtures name: … Electrolytes In 10% Dextrose Clinimix ... 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose ... 5% M In 20% Dextrose (dual Chamber) …
Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Approved
Matched Synonyms: … Rubella virus live antigen, A
Matched Description: … Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German ... strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus …
Matched Categories: … Antiinfectives for Systemic Use …
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone digoxigenin. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation. Its use in congestive...
Approved
Matched Synonyms: … 5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one …
Matched Description: … is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure ... A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone ... failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain …
Yellow fever vaccine is subcutaneously administered vaccination for the active immunization and prophylaxis of yellow fever in pediatric patients 9 months of age and older. The vaccine is prepared from the culture of 17D-204 strain of yellow fever virus in living avian leukosis virus-free (ALV-free) chicken embryos.
Approved
Matched Synonyms: … Yellow fever virus live antigen, A
Matched Description: … administered vaccination for the active immunization and prophylaxis of yellow fever in pediatric patients ... the culture of 17D-204 strain of yellow fever virus in living avian leukosis virus-free (ALV-free) chicken …
Matched Categories: … Antiinfectives for Systemic Use …
Barium sulfate is an inorganic compound with the chemical formula BaSO4. It displays low solubility in water, and is used in various chemical and industrial applications. It is a common contrast agent for diagonistic purposes and X-ray imaging; it is indicated radiographic examination of the gastrointestinal tract. Unlike other contrasting...
Approved
Matched Description: … solubility in water, and is used in various chemical and industrial applications. It is a common contrast ... contrast agent for diagonistic purposes and X-ray imaging; it is indicated radiographic examination of the ... stronger. Other therapeutic advantages of barium sulfate in diagnostic procedures include its low solubility …
Matched Products: … Baricon for Suspension ... Barosperse for Susp 95% ... E-Z-paque Powder for Suspension 95% …
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families. [PubChem]
Approved
Nutraceutical
Matched Synonyms: … (all-Z)-5,8,11,14,17-Eicosapentaenoic acid ... all-cis-5,8,11,14,17-eicosapentaenoic acid ... all-cis-5,8,11,14,17-icosapentaenoic acid …
Matched Description: … found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet ... diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular …
A synthetic progestational hormone with actions similar to those of progesterone and about twice as potent as its racemic or (+-)-isomer (norgestrel). It is used for contraception, control of menstrual disorders, and treatment of endometriosis. It is usually supplied in a racemic mixture (Norgestrel, 6533-00-2). Only the levonorgestrel isomer is...
Approved
Investigational
Matched Synonyms: … 10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one …
Matched Description: … treatment of endometriosis. It is usually supplied in a racemic mixture (Norgestrel, 6533-00-2). Only the ... A synthetic progestational hormone with actions similar to those of progesterone and about twice as potent ... racemic or (+-)-isomer (norgestrel). It is used for contraception, control of menstrual disorders, and …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].
Approved
Matched Products: … Almay Roll-On For Sensitive Skin - Fragrance-Free ... Altheus for Men ... Antiperspirant for Hands Feet Body Zero Sweat …
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Description: … A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or ... or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery. …
Matched Products: … Dobutamine Hydrochloride in Dextrose ... DOBUTamine Hydrochloride in Dextrose …
Simethicone is an orally administered antifoaming agent. It is mainly used to reduce gas from the gastrointestinal tract (GIT) in patients complaining from recurrent flatulence. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel. It exerts its action locally in the GIT, it is not absorbed into the blood...
Approved
Matched Description: … gastrointestinal tract (GIT) in patients complaining from recurrent flatulence. Simethicone is a mixture of polydimethylsiloxane ... hydrated silica gel. It exerts its action locally in the GIT, it is not absorbed into the blood stream …
Matched Products: … Ovol for Gas 180 Mg Capsule ... Ovol for Gas 180 Mg Tablet ... Ovol for Gas 80 Mg Tablet …
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Description: … A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations ... been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge …
Matched Products: … Acne Vanish Synergy for treatment of Acnes …
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular …
Matched Products: … Dipyridamole for Injection …
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl)-amide …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting ... IX is the lead component for potency and efficacy, particularly when used for the treatment of bleeding ... clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products …
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Matched Description: … A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the ... enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated …
Matched Mixtures name: … Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... Formula A.R.-th Dietary Supplement Zinc ... One A Day With Non-medicinal Echinacea Actyform …
Matched Products: … Port A Mins Super Zinc 15 ... Port A Mins Super Zinc 30 …
Triclocarban is an antibacterial agent that is particularly effective against Gram positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In September 2016, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products...
Approved
Matched Description: … *Staphylococcus aureus*. It is a bacteriostatic compound that has been found in antibacterial soaps and other ... other personal care products. In September 2016, the US FDA prohibited the marketing of over-the-counter …
Matched Products: … a.c.care Bees Foam Cleanser ... a.c.care Bees Foam Cleanser Troubled Skin …
Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray.
Approved
Matched Description: … anaesthetic found in Sucrets, an over the counter throat lozenge. It is also found in some varieties of …
Matched Products: … Sucrets for Kids …
Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent, inosine monophosphate dehydrogenase (IMPDH) inhibitor.
Approved
Investigational
Matched Products: … Mycophenolate Mofetil for Injection, USP …
Displaying drugs 526 - 550 of 607 in total