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Displaying drugs 51 - 75 of 5154 in total
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid …
Zilpaterol is a β2 adrenergic agonist. Under its trade name, Zilmax, it is used to increase the size of cattle and the efficiency of feeding them. Zilmax is produced by Intervet, a subsidiary of Merck & Co., and marketed as a "beef-improvement technology". Zilpaterol is typically fed in the last...
Vet approved
Matched Description: … Zilmax is produced by Intervet, a subsidiary of Merck & Co., and marketed as a "beef-improvement technology" ... Zilpaterol is a β2 adrenergic agonist. Under its trade name, Zilmax, it is used to increase the size ... the last three to six weeks of cattles lives, with a brief period before death for withdrawal, which allows …
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer ... mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … roxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7- …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration …
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Investigational
Matched Description: … oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells ... spinal neurons causing pain. Prostaglandins have a wide variety of actions, including, but not limited ... shown to improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect. It …
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia]
Approved
Matched Description: … Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia] …
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. [PubChem]
Approved
Investigational
Nutraceutical
Matched Description: … A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound …
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... Extra Once A Day ... Maximum Once A Day …
Matched Products: … D-biotin Tab 5mcg A Croquer …
An anthelmintic used in most schistosome and many cestode infestations.
Approved
Investigational
Vet approved
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of ... of obesity and associated co-morbidities, including type 2 diabetes. …
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects...
Approved
Investigational
Matched Description: … Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents ... tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There …
Matched Mixtures name: … Co-Veratrol …
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Synonyms: … Prostaglandin F2a tromethamine …
Matched Description: … prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline …
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma ... of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost …
Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and is in late phase trials in the United States as of early 2018. Roche, which makes Tamiflu,...
Approved
Investigational
Matched Description: … Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for ... for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and ... available in the United States [L1481]. Interestingly, a study has determined that administering Baloxavir …
Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for high cholesterol for adults whose LDL-cholesterol (LDL-C) is not controlled by diet and statin treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class of...
Approved
Matched Description: … Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for ... treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class …
Cobamamide is one of the active forms of vitamin B12 that is also known as adenosylcobalamin or dibencozide. This drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids. The principal biochemical participants are two coenzyme forms...
Approved
Matched Description: … available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective ... active co-enzyme forms, _methylcobalamin (MeCbl)_ and _adenosylcobalamin (AdCbl)_. There has been a shift ... therefore important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin …
Matched Products: … Co B12 …
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. …
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Investigational
Letrozole (INN, trade name Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding...
Approved
Investigational
Matched Description: … preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water ... formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids. Usage above …
Matched Mixtures name: … Kisqali Femara Co-pack ... Kisqali Femara Co-pack ... Kisqali Femara Co-pack …
Matched Products: … Co Letrozole …
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug...
Approved
Investigational
Vet approved
Matched Description: … with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent …
Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus needs to cleave the HIV polyprotein into its functional fragments.
Approved
Matched Description: … Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … in a premature termination of the trial. The FDA revised the doripenem label in 2014 to include a warning ... Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … responsible for acting as a co-factor to Factor IX. Activation of Factor IX leads to a cascade of signals that ... treatment of Hemophilia A, which is caused by mutations in the Factor VIII gene, leading to a functional deficiency ... Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation …
Matched Categories: … Hemophilia A
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its ... antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster …
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into...
Approved
Matched Description: … Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile …
Displaying drugs 51 - 75 of 5154 in total