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Displaying drugs 51 - 75 of 5048 in total
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. [PubChem]
Approved
Investigational
Matched Synonyms: … N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid …
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug...
Approved
Investigational
Vet approved
Matched Description: … with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent …
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and [DB09256] within the commercially available product "Teysuno". The main active ingredient in Teysuno is [DB09256],...
Approved
Matched Description: … ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug ... acts on rapidly dividing cancer cells. By mimicking a class of compounds called "pyrimidines" that are essential …
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer ... mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Synonyms: … Prostaglandin F2a tromethamine …
Matched Description: … prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline …
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its ... antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster …
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … roxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7- …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration …
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Approved
Investigational
Matched Description: … oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells ... spinal neurons causing pain. Prostaglandins have a wide variety of actions, including, but not limited ... shown to improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect. It …
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia]
Approved
Matched Description: … Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia] …
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of ... of obesity and associated co-morbidities, including type 2 diabetes. …
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects...
Approved
Investigational
Matched Description: … Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents ... tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There …
Matched Mixtures name: … Co-Veratrol …
Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and is in late phase trials in the United States as of early 2018. Roche, which makes Tamiflu,...
Approved
Investigational
Matched Description: … Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for ... for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and ... available in the United States [L1481]. Interestingly, a study has determined that administering Baloxavir …
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Approved
Investigational
Vet approved
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma ... of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost …
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Investigational
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide …
Cobamamide is one of the active forms of vitamin B12 that is also known as adenosylcobalamin or dibencozide. This drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids. The principal biochemical participants are two coenzyme forms...
Approved
Matched Description: … available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective ... active co-enzyme forms, _methylcobalamin (MeCbl)_ and _adenosylcobalamin (AdCbl)_. There has been a shift ... therefore important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin …
Matched Products: … Co B12 …
Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for high cholesterol for adults whose LDL-cholesterol (LDL-C) is not controlled by diet and statin treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class of...
Approved
Matched Description: … Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for ... treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class …
Experimental
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. …
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into...
Approved
Matched Description: … Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile …
Letrozole (INN, trade name Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding...
Approved
Investigational
Matched Description: … preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water ... formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids. Usage above …
Matched Mixtures name: … Kisqali Femara Co-pack ... Kisqali Femara Co-pack ... Kisqali Femara Co-pack …
Matched Products: … Co Letrozole …
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.
Approved
Matched Description: … Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial ... atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. …
Displaying drugs 51 - 75 of 5048 in total