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Displaying drugs 51 - 75 of 4673 in total
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Arimoclomol is an experimental drug compound developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. The orally administered drug is intended to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative disease with no effective treatment.
Investigational
Matched Description: … experimental drug compound developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California ... sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative disease with no effective treatment …
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Approved
Investigational
Vet approved
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and is in late phase trials in the United States as of early 2018. Roche, which makes Tamiflu,...
Approved
Investigational
Matched Description: … Baloxavir marboxil is a medication developed by Shionogi Co., a Japanese pharmaceutical company, for ... for treatment of influenza A and influenza B. The drug was approved for use in Japan in February 2018 and ... available in the United States [L1481]. Interestingly, a study has determined that administering Baloxavir …
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Investigational
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. [PubChem]
Approved
Investigational
Matched Synonyms: … N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid …
Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally....
Approved
Investigational
Matched Description: … structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has …
Cobamamide is one of the active forms of vitamin B12 that is also known as adenosylcobalamin or dibencozide. This drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids. The principal biochemical participants are two coenzyme forms...
Approved
Matched Description: … available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective ... active co-enzyme forms, _methylcobalamin (MeCbl)_ and _adenosylcobalamin (AdCbl)_. There has been a shift ... therefore important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin …
Matched Products: … Co B12 …
Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for high cholesterol for adults whose LDL-cholesterol (LDL-C) is not controlled by diet and statin treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class of...
Approved
Matched Description: … Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for ... treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class …
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Approved
Investigational
Matched Description: … oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells ... spinal neurons causing pain. Prostaglandins have a wide variety of actions, including, but not limited ... shown to improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect. It …
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia]
Approved
Matched Description: … Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia] …
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.
Approved
Matched Description: … Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial ... atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. …
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … roxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7- …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration …
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Synonyms: … Prostaglandin F2a tromethamine …
Matched Description: … prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline …
Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine.[A32912] All these components are produced by the fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine.[T90] The derivatives of this fungus are identified to be about 350 different substances from which the components...
Approved
Matched Synonyms: … co-dergocrine mesilate ... co-dergocrine mesylate ... co-dergocrine methanesulfonate …
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of ... of obesity and associated co-morbidities, including type 2 diabetes. …
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects...
Approved
Investigational
Matched Description: … Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents ... tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There …
Matched Mixtures name: … Co-Veratrol …
Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Approved
Matched Description: … Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering ... binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++. …
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma ... of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … in a premature termination of the trial. The FDA revised the doripenem label in 2014 to include a warning ... Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator …
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. …
AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs known as entry (fusion) inhibitors. Currently there is only one FDA-approved entry inhibitor, enfuvirtide (Fuzeon), that is available for the treatment of HIV infection. Several experimental entry inhibitors are now in early stage...
Investigational
Matched Description: … AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs …
Mevastatin or compactin is a cholesterol-lowering agent isolated from <i>Penicillium citinium</i>. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity ... During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It …
Displaying drugs 51 - 75 of 4673 in total