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Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. …
INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.
Investigational
Matched Description: … INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat ... treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus. …
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its ... Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names …
Matched Products: … Co Cilazapril …
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide …
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Description: … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential …
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma ... of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost …
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Synonyms: … Prostaglandin F2a tromethamine …
Matched Description: … prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline …
Empagliflozin is a sodium glucose co-transporter-2 (SGLT-2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes. SGLT2 co-transporters are responsible for reabsorption of glucose from the glomerular filtrate in the kidney. The glucuretic effect resulting from SGLT2 inhibition reduces...
Approved
Matched Description: … Empagliflozin is a sodium glucose co-transporter-2 (SGLT-2) inhibitor indicated as an adjunct to diet ... control in adult patients with type 2 diabetes. SGLT2 co-transporters are responsible for reabsorption of …
Calcium gluconate is a mineral supplement and medication. Supplementation is generally only required when there is not enough calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium...
Approved
Vet approved
Matched Description: … recommended by injection into a muscle. Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated ... Calcium gluconate is a mineral supplement and medication. Supplementation is generally only required ... of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate. …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … 3R)-3-Hydroxy-2-((S,e)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid …
Matched Description: … bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the ... Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It …
AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Investigational
Matched Description: … AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable …
Arimoclomol is an experimental drug compound developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. The orally administered drug is intended to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative disease with no effective treatment.
Investigational
Matched Description: … experimental drug compound developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California ... sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative disease with no effective treatment …
Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for high cholesterol for adults whose LDL-cholesterol (LDL-C) is not controlled by diet and statin treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class of...
Approved
Matched Description: … Alirocumab is a biopharmaceutical drug approved by the FDA in July 2015 as a second line treatment for ... treatment. It is a human monoclonal antibody administered by subcutaneous injection that belongs to a novel class …
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy [A19726]. It is not FDA-approved but available in...
Approved
Withdrawn
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and...
Investigational
Matched Description: … inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown ... availability of the drug in the patient's system through a decrease in clearance and an increase in maximal blood ... therapeutic drugs for treatment of anxiety, cancer, and a number of other serious conditions. …
Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally....
Approved
Investigational
Matched Description: … structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has …
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the …
Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.
Investigational
Matched Description: … (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. Biomed 101 binds to the leukotriene B4 receptor …
Cobamamide is one of the active forms of vitamin B12 that is also referred to as adenosylcobalamin or dibencozide. It is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 has essential physiological roles including DNA synthesis, myelin formation in the nervous system, red blood cell formation,...
Approved
Matched Description: … adenosylcobalamin or dibencozide. It is available as a nutritional supplement to prevent vitamin B12 deficiency …
Matched Products: … Co B12 …
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of ... of obesity and associated co-morbidities, including type 2 diabetes. …
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects...
Approved
Investigational
Matched Description: … Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents ... tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There …
Matched Mixtures name: … Co-Veratrol …
Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas that heads the noble gas group in the periodic table. Its boiling and melting points are the lowest among all the elements....
Approved
Investigational
Vet approved
Matched Description: … Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2 ... 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas that heads the noble gas group …
Matched Mixtures name: … Co-HE-O2-N2 Mixture …
Terazosin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and prostate enlargement. It works by blocking the action of adrenaline on smooth muscle of the bladder...
Approved
Matched Description: … Terazosin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia ... (BPH). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and prostate …
Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostaglandins have a wide variety of actions, including,...
Approved
Investigational
Matched Description: … oral prostaglandin E1 analog. Prostaglandins act on a variety of cells such as vascular smooth muscle cells ... spinal neurons causing pain. Prostaglandins have a wide variety of actions, including, but not limited ... shown to improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect. It …
Displaying drugs 51 - 75 of 4517 in total