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Displaying drugs 76 - 100 of 7358 in total
Fremanezumab is a genetically engineered humanized monoclonal antibody against human calcitonin gene-related peptide (CGRP) that is developed by Teva. This therapy is given as a monthly subcutaneous injection and ongoing clinical trials for the agent are for episodic and chronic migraine as well as cluster headaches.
Approved
Investigational
Matched Description: … This therapy is given as a monthly subcutaneous injection and ongoing clinical trials for the agent are ... for episodic and chronic migraine as well as cluster headaches [A33114]. ... Fremanezumab is a genetically engineered humanized monoclonal antibody against human calcitonin gene-related …
Nalmefene is a 6-methylene analogue of naltrexone and opioid system modulator but with no opioid activity [FDA Label]. It mediates a partial agonist effect on kappa receptors. It is primarily used in the management of alcohol dependence in adult patients in conjunction with continuous psychosocial support focused on treatment adherence...
Approved
Investigational
Withdrawn
Matched Description: … It mediates a partial agonist effect on kappa receptors [A31301]. ... hypotension by acting on the opioid receptor as an antagonist [FDA Label] under the trade name Revex for ... It is primarily used in the management of alcohol dependence in adult patients in conjunction with continuous …
Matched Categories: … Drugs Used in Alcohol Dependence ... Drugs Used in Addictive Disorders …
Manganese is a transition metal with a molar mass of 54.94g/mol. Manganese is considered critical for human health, and plays important roles in development, metabolism, and the antioxidant system. That said, excessive manganese intake is associated with manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and parkinsonian-like symptoms.
Approved
Nutraceutical
Matched Description: … Manganese is considered critical for human health, and plays important roles in development, metabolism ... Manganese is a transition metal with a molar mass of 54.94g/mol. ... That said, excessive manganese intake is associated with manganism, a neurodegenerative disorder that …
Matched Mixtures name: … Trace Elements for Injection - Liq IV ... Multivitamins and Minerals for Men ... One A Day Tab …
Triclocarban, with the chemical formula C13H9Cl3N2Ois an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic...
Approved
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products ... In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products …
Matched Products: … a.c.care Bees Foam Cleanser ... a.c.care Bees Troubled Skin Care 2 pcs Set ... a.c.care Bees Foam Cleanser Troubled Skin Care 2 pcs Set …
Formoterol is a long-acting (12 hours) beta2-agonist used in the management of asthma and/or chronic obstructive pulmonary disease (COPD). Inhaled formoterol works like other beta2-agonists, causing bronchodilatation through relaxation of the smooth muscle in the airway so as to treat the exacerbation of asthma.
Approved
Investigational
Matched Description: … Formoterol is a long-acting (12 hours) beta2-agonist used in the management of asthma and/or chronic ... works like other beta2-agonists, causing bronchodilatation through relaxation of the smooth muscle in
Matched Categories: … Drugs for Obstructive Airway Diseases …
Matched Products: … Foradil Dry Powder Capsules for Inhalation …
Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilizing activity at therapeutic dosages. Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which...
Approved
Matched Description: … Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short ... contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in
Matched Products: … Esmolol Hydrochloride In Sodium Chloride …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... pneumonia and to reiterate its safety and efficacy for its approved indications. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved
Matched Description: … Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. ... It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on ... Eucalyptus oil can be applied directly to the skin for pain and swelling of respiratory tract mucous …
Matched Mixtures name: … Mentholatum for Kids Cough Suppressant ... Icy Hot No Mess Vapor Cough Suppresant for Kids …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Cefotaxime is a third-generation cephalosporin antibiotic. ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Cefotaxime for Injection USP ... Cefotaxime Sodium for Injection BP ... Cefotaxime Sodium for Injection, BP …
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... In particular, erenumab-aooe is a human immunoglobulin G2 monoclonal antibody that has high affinity ... critical role in migraine [L2823]. …
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has decreased since the 1980s owing...
Approved
Withdrawn
Matched Description: … Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been ... and to slow disease progression in patients with rheumatoid arthritis [A32326]. ... Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius. Doxorubicin binds to nucleic acids, presumably by specific intercalation of the planar anthracycline nucleus with the DNA double helix.
Approved
Investigational
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius …
Matched Products: … Doxorubicin HCl for Inj. U.S.P. 10mg/vial ... Doxorubicin HCl for Inj. U.S.P. 50mg/vial ... Doxorubicin HCl for Inj. U.S.P. 150mg/vial …
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder.It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Description: … that is effective in the treatment of panic disorder and social anxiety disorder. ... Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant …
Matched Categories: … Monoamine Oxidase A Substrates …
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. ... option in combination with [DB08934] for the treatment of HCV genotypes 1a, 1b, 4, 5, and 6 [L852]. …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Erwinaze (asparaginase Erwinia chrysanthemi) contains an asparaginase specific enzyme derived from Erwinia chrysanthemi. Specifically, this L-asparaginase is a tetrameric enzyme consisting of four identical subunits, each having a molecular weight of about 35 kDa. The activity of Erwinaze is expressed in terms of International Units. It is an antineoplastic agent...
Approved
Investigational
Matched Description: … having a molecular weight of about 35 kDa [L149]. ... The activity of Erwinaze is expressed in terms of International Units. ... It is an antineoplastic agent and was FDA approved in November 19, 2011 [L149]. …
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Description: … A test of the diffusing capacity of the lungs for carbon monoxide (DLCO), is one of the most clinically ... Since 2002, FDA has favorably reviewed three GRAS notifications for carbon monoxide use in fresh meat ... This use of CO has been generally recognized as safe (GRAS) in several packaging applications for fresh …
Triethylenetatramine (TETA) is a highly selective divalent Cu(II) chelator and orphan drug that revereses copper overload in tissues. Its salt form, trientine (triethylenetetramine dihydrochloride or 2,2,2-tetramine) was introduced in 1969 as an alternative to D-penicillamine. It consists of a polyamine-like structure different from D-penicillamine, as it lack sulfhydryl groups. It...
Approved
Investigational
Matched Description: … It was previously approved by FDA in 1985 as second-line pharmacotherapy for Wilson's disease. ... copper overload in tissues. ... Triethylenetatramine (TETA) is a highly selective divalent Cu(II) chelator and orphan drug that revereses …
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched International brands: … Resonium A
Matched Description: … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Larotrectinib is an orally administered tropomyosin receptor kinase (Trk) inhibitor with demonstrated antineoplastic activity. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and Trk activation, which results in both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress Trk. Trk, a receptor...
Approved
Matched Iupac: … (3S)-N-{5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxypyrrolidine …
Matched Description: … Trk, a receptor tyrosine kinase activated by neurotrophins, is mutated in a variety of cancer cell types ... and plays an important role in tumor cell growth and survival. ... both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress …
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy.The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry which allows...
Approved
Matched Description: … A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in ... [L1139] Thus, technetium Tc-99m oxidronate is a powerful detection tool for abnormal osteogenesis by ... major clinical areas for diagnosis and/or therapy. …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated …
Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts....
Approved
Withdrawn
Matched Description: … Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) ... It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe ... Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Mequinol is a phenol used in various applications. It is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture of antioxidants, pharmaceuticals, plasticizers, and dyestuffs. It is found as an...
Approved
Matched Description: … Mequinol is a phenol used in various applications. ... It is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons ... It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment …
Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, it can...
Approved
Matched Iupac: … ethoxycarbonyl)oxy]-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of ... As a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. ... enhance patient compliance and simplified dosing compared to all other similar ocular steroids that …
Displaying drugs 76 - 100 of 7358 in total