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Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia]
Approved
Matched Description: … Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia] …
Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs are being developed by Sarawak Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared...
Investigational
Matched Synonyms: … (+)-calanolide A ... (+/-)-calanolide A
Matched Name: … Calanolide A
Matched Description: … Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found ... Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral ... found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs …
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and [DB09256] within the commercially available product "Teysuno". The main active ingredient in Teysuno is [DB09256],...
Approved
Matched Description: … ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug ... acts on rapidly dividing cancer cells. By mimicking a class of compounds called "pyrimidines" that are essential …
The chemical compound calcium acetate is the calcium salt of acetic acid. An older name is acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form. [Wikipedia]
Approved
Investigational
Matched Synonyms: … Ca(oac)2 …
Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus needs to cleave the HIV polyprotein into its functional fragments.
Approved
Matched Description: … Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus …
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer ... mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation....
Approved
Matched Synonyms: … enyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f]isobenzofuran-7-yl]carbamate …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral ... peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar …
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Approved
Matched Description: … Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering ... binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++. …
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … opropyl}-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18 …
Matched Description: … Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into ... Grazoprevir. Grazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 …
A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties.
Approved
Matched Description: … A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid …
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into...
Approved
Matched Description: … Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile …
Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. [PubChem]
Approved
Investigational
Matched Products: … Co Fluconazole-150 …
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Approved
Investigational
Matched Description: … A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … in a premature termination of the trial. The FDA revised the doripenem label in 2014 to include a warning ... Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator …
Anethole trithione was first developed in Japan by Nippon Sinyaku Co. as a bile secretion-stimulating drug. It was studied as a potential treatment for xerostamia and is being studied as an anticancer treatment.
Approved
Experimental
Matched Description: … Japan by Nippon Sinyaku Co. as a bile secretion-stimulating drug. It was studied as a potential treatment …
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Approved
Matched Description: … ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its ... antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster …
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and V...
Letrozole (INN, trade name Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding...
Approved
Investigational
Matched Description: … preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water ... formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids. Usage above …
Matched Mixtures name: … Kisqali Femara Co-pack ... Kisqali Femara Co-pack ... Kisqali Femara Co-pack …
Matched Products: … Co Letrozole …
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Approved
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors.
Approved
Investigational
Matched Description: … Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive …
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Memantine is an amantadine derivative with low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds preferentially to NMDA receptor-operated cation channels. It blocks the effects of excessive levels of glutamate that may lead to neuronal dysfunction. It is under investigation for the treatment of...
Approved
Investigational
Matched Description: … low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds …
Apremilast is a novel, orally available small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4). It is indicated in the treatment of active psoriatic arthritis in adults (approved by the FDA in March 2014) and moderate to severe plaque psoriasis (approved by the FDA in September 2014). PDE-4 is a...
Approved
Investigational
Matched Description: … By targeting a central component of the inflammatory signaling cascade rather than a single inflammatory ... Apremilast is a novel, orally available small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase ... (approved by the FDA in September 2014). PDE-4 is a cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase …
Mirtazapine is an antidepressant introduced by Organon International in 1996 used for the treatment of moderate to severe depression. Mirtazapine has a tetracyclic chemical structure and is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA). It is the only tetracyclic antidepressant that has been approved by the Food and...
Approved
Matched Synonyms: … 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine …
Matched Description: … depression. Mirtazapine has a tetracyclic chemical structure and is classified as a noradrenergic and specific …
Matched Products: … Co Mirtazapine …
Displaying drugs 76 - 100 of 4517 in total