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Displaying drugs 76 - 100 of 5044 in total
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Synonyms: … Prostaglandin F2a tromethamine …
Matched Description: … prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline …
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma ... of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost …
Memantine is an amantadine derivative with low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds preferentially to NMDA receptor-operated cation channels. It blocks the effects of excessive levels of glutamate that may lead to neuronal dysfunction. It is under investigation for the treatment of...
Approved
Investigational
Matched Description: … low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds …
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Synonyms: … roxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7- …
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration …
AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs known as entry (fusion) inhibitors. Currently there is only one FDA-approved entry inhibitor, enfuvirtide (Fuzeon), that is available for the treatment of HIV infection. Several experimental entry inhibitors are now in early stage...
Investigational
Matched Description: … AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … in a premature termination of the trial. The FDA revised the doripenem label in 2014 to include a warning ... Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator …
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched International brands: … Co-Pyronil …
Matched Description: … marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew …
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Approved
Nutraceutical
Matched Description: … also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases …
Matched Mixtures name: … Effervescent Vitamin C Powder With Ca and mg ... Buffered Vitamin C Powder With Ca Mg and K ... Port A Mins Super Cal-mag 300/150 With Vitamin D3 …
Matched Products: … ENA Actimineral A ... HANTAI 8030 Ca-D3 GOLD ... HANTAI 8030 Ca-D3 Premium …
Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors.
Approved
Investigational
Matched Description: … Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive …
Loxicodegol was developed by Nektar Therapeutics as an opioid analgesic with low abuse potential for the treatment of chronic pain. The lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997,...
Investigational
Matched Description: … due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid …
Strontium chloride (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. This kind of barrier protection for tooth hypersensitivity has, however, been...
Approved
Matched Description: … (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier …
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Approved
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity ... During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It …
A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem]
Approved
Investigational
Matched Description: … A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem] …
Matched Products: … Co Temazepam Capsules 15mg ... Co Temazepam Capsules 30mg …
Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second cell-based gene therapy that is FDA-approved but the first in the treatment of large B-cell lymphoma in...
Approved
Matched Description: … Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second ... Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse ... collected. The modified version of the T-cell expresses a new gene that targets and kills the lymphoma cells …
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy.An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can infect...
Approved
Matched Description: … virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very ... predictability, unlike retrovirus, as they associate with a specific region of the human cellular genome localized …
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. …
The chemical compound calcium acetate is the calcium salt of acetic acid. An older name is acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form. [Wikipedia]
Approved
Investigational
Matched Synonyms: … Ca(oac)2 …
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
Investigational
Arotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy.Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials.
Investigational
Matched Description: … beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied ... Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials …
Experimental
Matched Synonyms: … Cobalt cation (Co2+) ... Cobalt, ion (Co2+) …
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Description: … Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend ... percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize ... thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must …
Displaying drugs 76 - 100 of 5044 in total