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Displaying drugs 76 - 100 of 4673 in total
Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second cell-based gene therapy that is FDA-approved but the first in the treatment of large B-cell lymphoma in...
Approved
Matched Description: … Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second ... Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse ... collected. The modified version of the T-cell expresses a new gene that targets and kills the lymphoma cells …
An anthelmintic used in most schistosome and many cestode infestations.
Approved
Investigational
Vet approved
An anthelmintic used in most schistosome and many cestode infestations.
The chemical compound calcium acetate is the calcium salt of acetic acid. An older name is acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form. [Wikipedia]
Approved
Investigational
Matched Synonyms: … Ca(oac)2 …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … responsible for acting as a co-factor to Factor IX. Activation of Factor IX leads to a cascade of signals that ... treatment of Hemophilia A, which is caused by mutations in the Factor VIII gene, leading to a functional deficiency ... Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation …
Matched Categories: … Hemophilia A
A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem]
Approved
Investigational
Matched Description: … A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem] …
Matched Products: … Co Temazepam Capsules 15mg ... Co Temazepam Capsules 30mg …
Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus needs to cleave the HIV polyprotein into its functional fragments.
Approved
Matched Description: … Darunavir is a protease inhibitor used to treat HIV. It acts on the HIV aspartyl protease which the virus …
Letrozole (INN, trade name Femara®) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding...
Approved
Investigational
Matched Description: … preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water ... formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids. Usage above …
Matched Mixtures name: … Kisqali Femara Co-pack ... Kisqali Femara Co-pack ... Kisqali Femara Co-pack …
Matched Products: … Co Letrozole …
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into...
Approved
Matched Description: … Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile …
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell prol...
Arotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy.[T87] Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials.[L1168]
Investigational
Matched Description: … beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied ... Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials …
Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors.
Approved
Investigational
Matched Description: … Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive …
Investigational
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Approved
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched International brands: … Co-Pyronil …
Matched Description: … marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew …
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy [A19726]. It is not FDA-approved but available in...
Approved
Withdrawn
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co.
Experimental
Investigational
Matched Description: … Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes ... diabetes. It is being developed by Daiichi Sankyo Co. …
Erdosteine is a mucolytic. Erdosteine is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains 2 blocked sulfhydryl groups which are released following first-pass metabolism. The 3 active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus...
Investigational
Matched Description: … Erdosteine is a mucolytic. Erdosteine is a thiol derivative developed for the treatment of chronic obstructive ... more effectively than ambroxol 30mg twice daily. Co-administration of erdosteine and amoxicillin in patients ... compared with placebo. Erdosteine is associated with a low incidence of adverse events, most of which are …
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Approved
Matched Description: … ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its ... antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster …
Sevoflurane (2,2,2-trifluoro-1-[trifluoromethyl]ethyl fluoromethyl ether), also called fluoromethyl, is a sweet-smelling, non-flammable, highly fluorinated methyl isopropyl ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. [Wikipedia]
Approved
Vet approved
Matched Description: … fluoromethyl ether), also called fluoromethyl, is a sweet-smelling, non-flammable, highly fluorinated …
Memantine is an amantadine derivative with low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds preferentially to NMDA receptor-operated cation channels. It blocks the effects of excessive levels of glutamate that may lead to neuronal dysfunction. It is under investigation for the treatment of...
Approved
Investigational
Matched Description: … low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds …
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its ... Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names …
Matched Products: … Co Cilazapril …
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy.[L1094] An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can...
Approved
Matched Description: … virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very ... predictability, unlike retrovirus, as they associate with a specific region of the human cellular genome localized …
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Approved
Nutraceutical
Matched Description: … also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases …
Matched Mixtures name: … Effervescent Vitamin C Powder With Ca and mg ... Buffered Vitamin C Powder With Ca Mg and K ... Port A Mins Super Cal-mag 300/150 With Vitamin D3 …
Matched Products: … ENA Actimineral A ... HANTAI 8030 Ca-D3 GOLD ... HANTAI 8030 Ca-D3 Premium …
Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Investigational
Matched Description: … abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer ... mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity ... Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Apremilast is a novel, orally available small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4). It is indicated in the treatment of active psoriatic arthritis in adults (approved by the FDA in March 2014) and moderate to severe plaque psoriasis (approved by the FDA in September 2014). PDE-4 is a...
Approved
Investigational
Matched Description: … By targeting a central component of the inflammatory signaling cascade rather than a single inflammatory ... Apremilast is a novel, orally available small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase ... (approved by the FDA in September 2014). PDE-4 is a cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase …
Displaying drugs 76 - 100 of 4673 in total