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Displaying drugs 76 - 100 of 5154 in total
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Approved
Investigational
Vet approved
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched International brands: … Co-Pyronil …
Matched Description: … formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew …
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and [DB09256] within the commercially available product "Teysuno". The main active ingredient in Teysuno is [DB09256],...
Approved
Matched Description: … ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug ... acts on rapidly dividing cancer cells. By mimicking a class of compounds called "pyrimidines" that are essential …
Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine.All these components are produced by the fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine.The derivatives of this fungus are identified to be about 350 different substances from which the components of the...
Approved
Matched Synonyms: … co-dergocrine mesilate ... co-dergocrine mesylate ... co-dergocrine methanesulfonate …
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Description: … Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend ... percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize ... thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy. It is not FDA-approved but available in Japan...
Approved
Withdrawn
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide …
AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs known as entry (fusion) inhibitors. Currently there is only one FDA-approved entry inhibitor, enfuvirtide (Fuzeon), that is available for the treatment of HIV infection. Several experimental entry inhibitors are now in early stage...
Investigational
Matched Description: … AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs …
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.
Approved
Matched Description: … Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial ... atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. …
Gliquidone is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Approved
Investigational
Matched Description: … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ …
Memantine is an amantadine derivative with low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds preferentially to NMDA receptor-operated cation channels. It blocks the effects of excessive levels of glutamate that may lead to neuronal dysfunction. It is under investigation for the treatment of...
Approved
Investigational
Matched Description: … low to moderate-affinity for NMDA receptors. It is a noncompetitive NMDA receptor antagonist that binds …
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy.An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can infect...
Approved
Matched Description: … virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very ... predictability, unlike retrovirus, as they associate with a specific region of the human cellular genome localized …
A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent.
Approved
Investigational
Matched Description: … A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. …
Matched Products: … Co Temazepam Capsules 15mg ... Co Temazepam Capsules 30mg …
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity ... During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It …
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Approved
Nutraceutical
Matched Description: … also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases …
Matched Mixtures name: … Port A Mins Super Calcium 375 With Vitamin D3 ... Port A Mins Super Calcium 750 With ... Formula A.R.-th Dietary Supplement …
Matched Products: … ENA Actimineral A ... HANTAI 8030 Ca-D3 GOLD ... HANTAI 8030 Ca-D3 Premium …
Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second cell-based gene therapy that is FDA-approved but the first in the treatment of large B-cell lymphoma in...
Approved
Matched Description: … Diffuse large B-cell lymphoma (DLBCL), which is a type of a non-Hodgkin lymphoma (NHL). It is the second ... Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T cell therapy for the treatment of Diffuse ... collected. The modified version of the T-cell expresses a new gene that targets and kills the lymphoma cells …
Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Natalvirt Ca
Experimental
Matched Synonyms: … Cobalt cation (Co2+) ... Cobalt, ion (Co2+) …
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
Loxicodegol was developed by Nektar Therapeutics as an opioid analgesic with low abuse potential for the treatment of chronic pain. The lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997,...
Investigational
Matched Description: … due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid …
Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors.
Approved
Investigational
Matched Description: … Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive …
Investigational
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Description: … Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to …
Displaying drugs 76 - 100 of 5154 in total