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Displaying drugs 76 - 100 of 5297 in total
Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. The characteristics of testosterone cypionate and testosterone enanthate are very similar, therefore both of them...
Approved
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta …
Manganese is a transition metal with a molar mass of 54.94g/mol. Manganese is considered critical for human health, and plays important roles in development, metabolism, and the antioxidant system. That said, excessive manganese intake is associated with manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and parkinsonian-like symptoms.
Approved
Nutraceutical
Matched Description: … Manganese is a transition metal with a molar mass of 54.94g/mol. ... That said, excessive manganese intake is associated with manganism, a neurodegenerative disorder that …
Matched Mixtures name: … One A Day Tab ... A/o-26 - Caplet ... A.R.T.H. Away Formula …
Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Matched Description: … Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group ... Chromium deficiency has been associated with a diabetic-like state, impaired growth, decreased fertility ... Chromium chloride is available as an intravenous injection for use as a supplement to intravenous solutions …
Matched Mixtures name: … A.M. Formula ... Extra Once A Day ... Maximum Once A Day …
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. …
A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see mesalamine) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
Approved
Matched Description: … A drug that is used in the management of inflammatory bowel diseases. …
Matched Products: … S.A.S. Enteric 500mg …
Doxepin is a dibenzoxepin-derivative tricyclic antidepressant (TCA). Structurally similar to phenothiazines, TCAs contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, doxepin does not affect mood or arousal, but may cause sedation. In depressed individuals, doxepin exerts a positive effect on mood....
Approved
Investigational
Matched Description: … Doxepin is a dibenzoxepin-derivative tricyclic antidepressant (TCA). ... In depressed individuals, doxepin exerts a positive effect on mood. ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … necessary co-factor in the body. ... cellular replacement for the co-factor THF, thereby preventing these toxic side effects. ... This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible …
Matched Products: … Leucovorin Ca Inj (pharm. Bulk Vial) 10mg/ml …
A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent.
Approved
Investigational
Matched Description: … A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. …
Matched Products: … Co Temazepam Capsules 15mg ... Co Temazepam Capsules 30mg …
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Description: … It is also used in laboratory research as a protein denaturant. ... It is found in the urine as a normal product of protein metabolism. ... A strong organic base existing primarily as guanidium ions at physiological pH. …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index …
Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health.
Approved
Matched Description: … It may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential …
Matched Mixtures name: … One-A-day Advance Men's ... Super-A Vitamins With Selenium Dietary Supplement …
CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … This antibody was used to generate a recombinant immunotoxin in which a stabilized Fv segment by a disulfide ... CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia ... bond is fused to the _Pseudomonas_ exotoxin A (PE38) which does not have the cell-binding portion. …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... the World Health Organization's List of Essential Medicines, the most important medications needed in a
Matched Mixtures name: … Delflex Perit.dial.soL.1.5%dex.low Ca Low mg ... Delflex Perit.dial.soL.2.5%dex.low Ca Low mg ... A-C-D Solution …
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy.The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry which allows...
Approved
Matched Description: … A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in ... Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical. ... [L1139] Thus, technetium Tc-99m oxidronate is a powerful detection tool for abnormal osteogenesis by …
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon. Also known as ST-246, Tecovirimat is the first approved drug for smallpox,. Tecovirimat has been studied for the treatment of...
Approved
Investigational
Matched Description: … The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, ... However, there have been longstanding concerns that smallpox may be used as a bioweapon [L3614]. …
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately. Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute. Elsewhere in English speaking countries...
Approved
Withdrawn
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Approved
Nutraceutical
Vet approved
Matched Description: … A member of the vitamin B family that stimulates the hematopoietic system. …
Matched Mixtures name: … Co-Veratrol ... Natalvirt Ca ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes smooth muscle, stimulates cardiac muscle, stimulates diuresis, and appears to be useful in the treatment of...
Approved
Matched Description: … A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. ... Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness …
Matched Mixtures name: … A.C. & C. 8mg ... A.C. & C. 8 mg ... Saridon - A
Capmatinib has been used in trials studying the treatment of Melanoma, Gliosarcoma, Solid Tumors, Colorectal Cancer, and Hepatic Impairment, among others.
Approved
Investigational
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … ]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl}-1-azabicyclo[3.2.0]hept
Matched Description: … Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... found that doripenem carried an increased risk of death and lower clinical cure rates, resulting in a ... The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated …
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Description: … In depressed individuals, amoxapine exerts a positive effect on mood. ... See toxicity section below for a complete listing of side effects. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations. It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage. The UV-filter substance, sulisobenzone (BP-4) is widely used an...
Approved
Matched Description: … As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and ... The benzophenones are a group of aromatic ketones that have both pharmaceutical and industrial applications …
Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures. Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction...
Approved
Investigational
Matched Description: … Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of ... Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset ... Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position. It is a schedule III drug in the U.S.
Approved
Illicit
Matched Description: … It is a schedule III drug in the U.S. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … However there is no antidote available in the event of a major bleed. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence ... some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and a
Displaying drugs 76 - 100 of 5297 in total