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Displaying drugs 101 - 125 of 11560 in total
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to ... bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines ... Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the …
Matched Products: … Pasurta 70mg/ml Solution for Injection in a Prefilled Syringe …
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads …
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar …
Matched Products: … N/A ... Zoledronic Acid - A ... Zoledronic Acid Injection A
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Description: … Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. ... other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays improved oral absorption and a ... it enters bacteria and parasites, secnidazole is activated by bacterial or parasitic enzymes to form a
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Description: … A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Matched Products: … TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Description: … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. …
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Antiphlogistine Rub A-535 Capsaicin Gel ... Antiphlogistine Rub A-535 Capsaicin Liquid …
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. …
Matched Mixtures name: … Plasma-Lyte A ... PLASMA-LYTE A INJECTION ... Plasma-lyte A Injection …
Approved
Vet approved
Matched Iupac: … 1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Mixtures name: … Alcortin A ... Alcortin A
Matched Products: … Poli-A
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Description: … Like citric acid, it has a sour taste. …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A
Matched Categories: … Compounds used in a research, industrial, or household setting …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. …
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Description: … and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention ... associated with many stimulant-associated side effects and an increase in abuse potential, which is a
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative ... Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules ... [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Lax-A-day ... Lax-A-day Men ... Lax-A-day Pharma …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … It is a structural analog of [doxepin], which has a minimal anti-allergic activity. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... [L6790] Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief …
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell ... It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA …
Matched Products: … Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Enbrel Solution for Injection in a Pre-filled Syringe 50mg ... Enbrel Solution for Injection in a Pre-Filled Syringe 25mg …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … either as a co-infection or super-infection in a HBsAg carrier. ... It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Description: … Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment ... [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity ... [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase ... Compared to [sildenafil] and [tadalafil], vardenafil is a more potent inhibitor of PDE5; however, its ... [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension …
Matched Products: … Vardenafil 1 A Pharma 5 mg - Filmtabletten ... Vardenafil 1 A Pharma 10 mg - Filmtabletten ... Vardenafil 1 A Pharma 20 mg - Filmtabletten …
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched International brands: … A Di Xian ... A Gan Ding …
Displaying drugs 101 - 125 of 11560 in total