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Displaying drugs 101 - 125 of 13625 in total

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical ... It is used in a number of health and beauty products including hair care products such as shampoo, conditioner ... for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing …
Matched Mixtures name: … Childrens Mylicon All in One Tummy Relief for Kids ... QYO QYO Tangerine Bright Moist All In One Cream ... A AND A Diaper Rash cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sonatural for Men Stay Young All In One Fluid ... Mizon All In One Snail Repair ... Novana All-In-One One Step Perineal …

Von Willebrand factor human

The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … [A32262] Exogenous sources of vWF are used to restore functional levels of vWF in blood disorders associated ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood ... [L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Optivate POWDER FOR INJECTION …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil ... samples from Mount Ararat in Turkey. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Daptomycin in Sodium Chloride ... CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in ... Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which ... antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in …
Matched Mixtures name: … CEFAZIME FOR INJECTION 1 g/vial …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFTAZIDIME KABI POWDER FOR SOLUTION FOR INJECTION 2G/VIAL ... CEFTAZIDIME KABI POWDER FOR SOLUTION FOR INJECTION 1G/VIAL ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …

Susoctocog alfa

Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … In a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients ... the treatment's efficacy and safety by measuring factor VIII activity levels in addition to clinical ... partial thromboplastin time (aPTT) assay, a conventional in vitro test for biological activity of factor …

Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... for a variety of clinical situations requiring analgesia. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for …
Matched Mixtures name: … All Night Pain Relief PM ... All Day Sinus and Cold D ... All Day Sinus and Cold D …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Antiinflammatory Products for Vaginal Administration ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … Naproxen All day relief for pain ... Naproxen Caplets All day relief for pain ... A-NOX FORT 550 MG TABLET, 20 ADET …

Desoxyribonuclease

Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Synonyms: … Deoxyribonuclease A …
Matched Description: … Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes ... It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) ... LYXUMIA (SOLUTION FOR INJECTION 10 MCG) …

Exagamglogene autotemcel

Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a …
Matched Description: … red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease ... [L49246] In January 2024, exagamglogene autotemcel received an additional FDA approval for the treatment …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... [L43115] Betaine reduces plasma homocysteine levels in patients with homocystinuria. …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin ... Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin for Injection ... Bivalirudin in 0.9% Sodium Chloride ... ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML) …

Capsaicin

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical ... Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for …
Matched Mixtures name: … Arthricare for Women Multi-action ... Littles All Natural Arthritic Pain Relief ... Tianhe Gutong Tiegao (in Polyisobutylene Carrier) …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Topical Products for Joint and Muscular Pain …
Matched Products: … Antiphlogistine Rub A-535 Capsaicin Gel ... Antiphlogistine Rub A-535 Capsaicin Liquid ... Arthricare for Women Quick Drying …

Indocyanine green acid form

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Description: … Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. ... Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized ... Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Spy Agent Green Kit for Spy Elite ... Spy Agent Green Kit for Spy-phi ... Indocyanine Green for Injection Kit …

Alginic acid

Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Description: … Available in different types of salt, alginic acid has been used in a variety of uses in food, cosmetics ... been used worldwide for over 30 years [A32961]. ... and pharmaceu-tical products for over 100 years [A32961]. …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Description: … Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in ... double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … TAMIPOOL FOR INJECTION ... Insur-all Vitamin Supplement ... One A Day Tab …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Description: … A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative …
Matched Mixtures name: … All-Natural Pen Spray ... Urologic G for Irrigation ... Urologic G for Irrigation …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Disinfectants (For Agents Used on Object) …
Matched Products: … Lysol Simply Disinfectant All Purpose Cleaner …

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. ... Artesunate is indicated for the initial treatment of severe malaria. ... [L14099] The World Health Organization recommends artesunate as first line treatment for severe malaria …
Matched Products: … ARTESUNATE FOR INJECTION ... ARTESUN POWDER FOR INJECTION 60 MG …

D-alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … who may demonstrate a genuine deficiency in vitamin E. ... Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals ... indications for vitamin E use. …
Matched Mixtures name: … Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Gamolenic acid

Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … all-cis-6,9,12-octadecatrienoic acid …
Matched Description: … Evening primrose oil has been investigated for clinical use in menopausal syndrome, diabetic neuropathy ... It is converted to [DB00154], a biosynthetic precursor of monoenoic prostaglandins such as PGE1. ... Gamolenic acid is also found in some fungal sources and also present naturally in the form of triglycerides …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus ... Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there …
Matched Mixtures name: … For-2 ... CERNEVIT FOR INJECTION ... Multivitamins for Children …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … YYUX Organic Liquid Vitamin D3 Drops For Baby 0-3 years 400 IU ... YYUX Organic Liquid Vitamin D3 Drops For Kids 4 plus years 600 IU …

Niacin

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Multi-force for Women Tab ... Doctor's Choice Brand for Men …
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …

Lovastatin

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin ... [A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark ... for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD as well …
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … because even though its presence is vital in the body, a deficiency in this molecule does not translate ... [L2560] Inositol can be found as an ingredient of OTC products by Health Canada but all current product ... It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin …
Matched Mixtures name: … Insur-all Vitamin Supplement ... Harvest Of Values All B Complex Tab ... One A Day Tab …

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia ... The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium ... , in buffer solutions, and in fertilizers and explosives. …
Matched Mixtures name: … Plasma-Lyte A ... Elliott's Solution A ... PLASMA-LYTE A INJECTION …
Matched Products: … Kcl Solution A 20% ... Potassium Chloride for Oral Solution ... Potassium Chloride for Hemodialysis 7.55 …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … effects of khelline when he found that all of his samples, dissolved in valproic acid, exerted a similar ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …
Matched Mixtures name: … Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 250 mg Retardgranulat in Beuteln …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … 400 mg Powder for injection / infusion ... SODIUM VALPROATE AGUETTANT SOLUTION FOR INJECTION 400MG/4ML ... SODIUM VALPROATE WOCKHARDT SOLUTION FOR INJECTION OR INFUSION 100mg/ml …
Displaying drugs 101 - 125 of 13625 in total