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Displaying drugs 151 - 175 of 13626 in total

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Description: … This drug is used as a contrast agent in diagnostic x-ray procedures. ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation ... combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Baricon for Suspension ... Barosperse for Susp 95% ... Tonopaque for Suspension 95% …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … subcutaneously for the treatment of MDS of all French-American-British (FAB) subtypes. ... [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved ... Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. …
Matched Products: … VIDAZA POWDER FOR SUSPENSION FOR INJECTION 100 MG /VIAL ... Azacitidine For ... Vidaza powder for suspension for injection 100mg/vial …

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. ... [A229013] Oxytocin also serves a role in metabolic homeostasis and cardiovascular regulation. ... [A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml …

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Cho-A Care Lot 1% …
Matched Categories: … Medications that reduce magnesium levels ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Corticosteroids for Systemic Use ... Corticosteroids for Systemic Use, Plain ... Corticosteroids for Local Oral Treatment …
Matched Products: … Hydrocortisone 1% in Absorbase ... SKIN A COOL Hydrocortisone Anti-Itch ... Healerz for Itches …

Bendamustine

Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl...
Approved
Investigational
Matched Description: … Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia ... alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... RIBOMUSTIN 25MG/VIAL POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... RIBOMUSTIN 100MG/VIAL POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

Sodium acetate

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … It can be used also in metabolic acidosis and for urine alkalinization. ... It is mainly indicated to correct sodium levels in hyponatremic patients. ... Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. …
Matched Mixtures name: … Plasma-Lyte A ... PLASMA-LYTE A INJECTION ... Plasma-lyte A Injection …

Ketorolac

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Description: … it a useful opioid sparing agent. ... Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral ... [L6358][L6508][L11055][L3674][L11070] It's analgesic properties make it a useful pain management …
Matched Products: … Xevolac 10 mg/ml Solution for Injection ... Xevolac 30 mg/ml Solution for Injection ... XEVOLAC SOLUTION FOR INJECTION 30 MG/ML …

Atomoxetine

Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Description: … and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention ... role for the glutamatergic system in the pathophysiology of ADHD. …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Rifaximin

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not ... pass the gastrointestinal wall into the circulation as is common for other types of orally administered ... syndrome (IBS-D) in adult women and men. …
Matched Categories: … Antibiotics for Topical Use …
Matched Products: … RIFAXIGAL® 100MG/5ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. …
Matched Products: … DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG ... DUROGESIC SMAT 50 A 8.4MG …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... useful contrast agent for liver MRI. ... contrast agent (GBCA) used primarily for MR imaging of the liver. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …

Testosterone undecanoate

Testosterone undecanoate is the ester prodrug of testosterone and has a mid-chain fatty acid at the carbon 17β position. It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for...
Approved
Investigational
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … formulations are indicated for testosterone replacement therapy in adult males with hypogonadism. ... [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal ... Testosterone replacement therapy aims to restore the levels of testosterone, thereby improving symptoms …
Matched Products: … NEBIDO 1000MG SOLUTION FOR INJECTION …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension ... [A258318] The FDA approved the use of vardenafil for the treatment of erectile dysfunction in 2003 ... selectivity for other PDE isoforms is lower than the one detected for tadalafil. …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Vardenafil 1 A Pharma 5 mg - Filmtabletten ... Vardenafil 1 A Pharma 10 mg - Filmtabletten ... Vardenafil 1 A Pharma 20 mg - Filmtabletten …

Albendazole

A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched International brands: … Ben-A …
Matched Description: … A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against …
Matched Products: … A-zole Suspension (Strawberry) 200mg/5ml …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol ... It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Other esmolol formulations are still available for use.[L43942] …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... compounds due to its minimal protection against UV-A wavelengths. ... Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … SIMPLI DAY All In One SmartCream SPF 42 ... Queens Rose Whole In One Sunblock ... Aqua Fusion SPF 15 Peau Normale A Seche …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Covergirl Queen Collection All Day Flawless 3in1 Foundation Broad Spectrum SPF 20 - Q800 Sand …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections ... by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections. ... In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Migalastat

Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Description: … a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). ... for the treatment of Fabry disease in adults who have amenable GLA variants. ... This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …

Hydroxypropyl cellulose

Hydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions,...
Approved
Matched International brands: … A-Gel …
Matched Description: … Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. ... lubricant for artificial eyes. ... As a food additive, hydroxypropyl cellulose is used as a thickener and as an emulsion stabilizer. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Description: … It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory ... It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria ... Tacrolimus is chemically known as a macrolide. …
Matched Categories: … Medications that reduce magnesium levels ... Agents for Dermatitis, Excluding Corticosteroids ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … Tacrolimus 0.1% In Pseudocatalase ... PROGRAF CONCENTRATE FOR INFUSION 5MG/ML ... PROGRAF CONCENTRATE FOR INFUSION 5 mg/ml …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … A barbiturate that is administered intravenously for the induction of general anesthesia or for the production ... It has been used in neurosurgical patients to reduce increased intracranial pressure. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANES 1.0 (THIOPENTAL SODIUM FOR INJECTION BP) …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. ... A cell-cycle phase nonspecific alkylating antineoplastic agent. ... Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a …
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK ... Carmustine for Injection USP ... STINARED® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. ... Acromegaly is a life-threatening disease requiring life-long management. …
Matched Products: … SANDOSTATIN LAR FOR INJECTION 10 mg ... SANDOSTATIN LAR FOR INJECTION 20 mg ... SANDOSTATIN LAR FOR INJECTION 30 mg …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Medications that reduce magnesium levels ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … Quinidine Gluconate for Inj 80mg/ml USP …

Doripenem

Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... pneumonia and to reiterate its safety and efficacy for its approved indications. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Powder for Injection 500mg ... DORIBAX 500 MG (Doripenem) for Injection …
Displaying drugs 151 - 175 of 13626 in total