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Displaying drugs 176 - 200 of 13615 in total
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Description: … and a cause for significant concern. ... months or longer and may not be effective, the pretomanid-containing regimen allows for a more efficacious ... Research in recent years has been geared toward the development of novel therapies that target persistent …
Matched Categories: … Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Description: … hemoglobin levels and is considered to be a useful, cost-effective treatment option for managing type ... to lower blood glucose levels. ... First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class …
Matched Categories: … Drugs Used in Diabetes …
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Description: … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin …
Matched Mixtures name: … ALVOCLAV POWDER FOR SOLUTION FOR INJECTION 1.2G/VIAL ... Co-Amoxiclav for Injection 1.2g ... Hovid Clamovid for Injection 0.6g …
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. ... A cell-cycle phase nonspecific alkylating antineoplastic agent. ... Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK ... Carmustine for Injection USP ... STINARED® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... pneumonia and to reiterate its safety and efficacy for its approved indications. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Powder for Injection 500mg ... DORIBAX 500 MG (Doripenem) for Injection …
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Description: … It is not approved for use in the United States. ... to produce factor VIII protein and increase the levels of active factor VIII in blood. ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for
Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... This drug is a complex of iron (III) hydroxide and derisomaltose. ... Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January …
Matched Products: … Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules ... MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML …
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Description: … [A261730] Copanlisib was granted accelerated approval by the FDA in September 2017 for the treatment ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth ... Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Products: … HYDROXO-B12 SOLUTION FOR INJECTION 1MG/1ML …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … drug represents a therapeutic alternative for patients with cancers that have developed imatinib-resistance ... [A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML ... [A11377,A33432] Dasatinib also inhibits a spectrum of kinases involved in cancer, including several SRC-family …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … [A237505] TBE often manifests in a biphasic manner, with patients experiencing a flu-like illness followed ... A237520] While some patients recover fully following neurological TBE, neurological sequelae can last for ... [A237520, A237525] A second very similar vaccine, Encepur, followed in 1991. …
Matched Products: … FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze ... FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer Fertigspritze …
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men ... with osteoporosis at high risk for fracture in September 2012. ... Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … XGEVA 120mg Solution for Injection ... XGEVA Solution for Injection 120 mg/vial ... Prolia Solution for Injection 60mg Pre-filled Syringe …
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive ... [L15536] Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use …
Matched Products: … ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …
Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … topical OTC preparations and has been studied for management of different models of neuropathic pain ... It is commonly used as a culinary spice. ... Capsicum oleoresin is contained in pepper sprays when suspended in water, and acts an active lachrymatory …
Matched Mixtures name: … Arthricare for Women Ultra Strength …
Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 ... Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... It is a heterodimeric glycoprotein made up of monomeric units. …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Description: … As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by ... [L41715] The Vantas product was approved by the FDA in October 2004 for the palliative treatment of this ... the FDA in May 2007). …
Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam. In the US, it presents a Status class I by the...
Approved
Investigational
Matched Description: … It is used in the UK as a treatment for migraine under the name of Clotam. ... [L1292] In the US, it presents a Status class I by the FDA. ... By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of …
Matched Products: … TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS ... Tolfine Solution for Injection 4.0% W/V …
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Description: … (ESA) with a longer half-life than erythropoietin. ... Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 200MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 150MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 100MCG/0.3ML …
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Desferal 500mg Powder for Solution for Injection ... Deferoxamine Mesylate for Injection ... DBL DESFERRIOXAMINE MESYLATE FOR INJECTION BP 500 mg/vial …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. ... , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG ... BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection …
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … It is available in topical products as a skin soothing agent. ... Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor ... Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities …
Matched Mixtures name: … Infinite Aloe All-IN-one Skin Care …
Matched Products: … 3-In-1 Relief CVS ... A Bit Hippy ... TMC-A Hair Tonic …
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a ... Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia …
Matched Products: … FRESOFOL MCT/LCT EMULSION FOR INJECTION OR INFUSION IN PRE-FILLED SYRINGE 2% ... Propofol "Fresenius" 1 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze ... Propofol "Fresenius" 2 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated …
Matched Products: … innohep 8.000 IE/0,4 ml Injektionslösung in einer Fertigspritze ... innohep 10.000 IE/0,5 ml Injektionslösung in einer Fertigspritze ... innohep 12.000 IE/0,6 ml Injektionslösung in einer Fertigspritze …
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Description: … It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. ... It is a third-generation vinca alkaloid. ... a strong influence of genetics on the clearance of this drug [L2002]. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Vinorelbine Tartrate for Injection …
Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Description: … [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June ... It was first used in cattle followed by an approved use in general animals. ... It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of …
Matched Mixtures name: … Advocate Spot-on Solution for Small Dogs ... Advocate Spot-on Solution for Large Dogs ... Advocate Spot-on Solution for Medium Dogs …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 176 - 200 of 13615 in total