Displaying drugs 1 - 25 of 15273 in total
Indium In-111 pentetreotide
Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Approved
Investigational
Matched Synonyms: … Indium In 111 Pentreotide ... Indium In 111 pentetreotide ... Indium In-111 pentetreotide …
Matched Name: … Indium In-111 pentetreotide …
Matched Iupac: … (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl ... -pentaazacycloicosa-5,8,11,14,17-pentaen-19-yl]-C-hydroxycarbonimidoyl}-2-phenylethyl)-C-hydroxycarbonimidoyl ... ]-6,12,15,18-tetrahydroxy-7-(1-hydroxyethyl)-13-[(1H-indol-3-yl)methyl]-9-oxido-1,2-dithia-5,8,11,14,17 …
Matched Description: … Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS …
Matched Name: … Indium In-111 pentetreotide …
Matched Iupac: … (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl ... -pentaazacycloicosa-5,8,11,14,17-pentaen-19-yl]-C-hydroxycarbonimidoyl}-2-phenylethyl)-C-hydroxycarbonimidoyl ... ]-6,12,15,18-tetrahydroxy-7-(1-hydroxyethyl)-13-[(1H-indol-3-yl)methyl]-9-oxido-1,2-dithia-5,8,11,14,17 …
Matched Description: … Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … a deficiency in GAA. ... [A232955, A232960] In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP ... for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by …
Matched Description: … a deficiency in GAA. ... [A232955, A232960] In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP ... for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by …
Ergocalciferol
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Synonyms: … (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- …
Matched Description: … Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in ... double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … Swical-energy 3e Age ... Mvc 9 Plus 3 Inj ... TAMIPOOL FOR INJECTION …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- …
Matched Description: … Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in ... double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … Swical-energy 3e Age ... Mvc 9 Plus 3 Inj ... TAMIPOOL FOR INJECTION …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched International brands: … Chocola A …
Matched Synonyms: … all-trans-vitamin A alcohol ... all-trans-retinol ... all-trans-retinyl alcohol …
Matched Name: … Vitamin A …
Matched Description: … Dietary vitamin A is derived from a variety of carotenoids found in plants. ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Salts cas: … 79-81-2 …
Matched Mixtures name: … For-2 ... FLAVETTES DAILY PLUS TABLET F/C ... Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Salts name: … Vitamin A acetate ... Vitamin A palmitate …
Matched Categories: … Retinoids for Topical Use in Acne ... Compounds used in a research, industrial, or household setting ... Tests for Fat Absorption ... Vitamin A ... Anti-Acne Preparations for Topical Use …
Matched Products: … VITAMIN A (S/C TABLET ) ... C-Mask Pack ... VIT A N …
Matched Synonyms: … all-trans-vitamin A alcohol ... all-trans-retinol ... all-trans-retinyl alcohol …
Matched Name: … Vitamin A …
Matched Description: … Dietary vitamin A is derived from a variety of carotenoids found in plants. ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Salts cas: … 79-81-2 …
Matched Mixtures name: … For-2 ... FLAVETTES DAILY PLUS TABLET F/C ... Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Salts name: … Vitamin A acetate ... Vitamin A palmitate …
Matched Categories: … Retinoids for Topical Use in Acne ... Compounds used in a research, industrial, or household setting ... Tests for Fat Absorption ... Vitamin A ... Anti-Acne Preparations for Topical Use …
Matched Products: … VITAMIN A (S/C TABLET ) ... C-Mask Pack ... VIT A N …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … MTC-DOX for Injection ... (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. ... [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXOCCORD CONCENTRATE FOR SOLUTION FOR INFUSION 2 MG/ML ... CAELYX CONCENTRATE FOR INFUSION 2 mg/ml ... DOXORUBICIN-ACTAVIS CONCENTRATE FOR SOLUTION FOR INFUSION 2 MG/ML …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. ... [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXOCCORD CONCENTRATE FOR SOLUTION FOR INFUSION 2 MG/ML ... CAELYX CONCENTRATE FOR INFUSION 2 mg/ml ... DOXORUBICIN-ACTAVIS CONCENTRATE FOR SOLUTION FOR INFUSION 2 MG/ML …
DL-alpha tocopheryl acetate
Approved
Experimental
Matched Synonyms: … all-rac-alfa-tocopheryl acetate ... all-rac-alpha-tocopheryl acetate …
Matched Iupac: … 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Mixtures name: … Vitamins A, C & E Cap. ... Fizz Multivitamins for Kids W C Loz ... Beta C and E Tab …
Matched Categories: … Vitamin E …
Matched Products: … Vitamin E Cap 400iu ... VITAMIN E 400 IU ... Vitamine E Cap 25unit …
Matched Iupac: … 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Mixtures name: … Vitamins A, C & E Cap. ... Fizz Multivitamins for Kids W C Loz ... Beta C and E Tab …
Matched Categories: … Vitamin E …
Matched Products: … Vitamin E Cap 400iu ... VITAMIN E 400 IU ... Vitamine E Cap 25unit …
Mitapivat
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Synonyms: … Pkr-in-1 …
Matched Description: … Mitapivat is a novel, first-in-class pyruvate kinase activator. ... It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival ... hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare, inherited disorder leading …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Mitapivat is a novel, first-in-class pyruvate kinase activator. ... It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival ... hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare, inherited disorder leading …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Beta carotene
Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Synonyms: … all-trans-β-carotene …
Matched Iupac: … 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex …
Matched Description: … It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits. ... [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. ... [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS). …
Matched Mixtures name: … For-2 ... Vitamins A, C & E Cap. ... Eden With Vitamins A, C, and E …
Matched Categories: … Vitamin A ... Protectives Against UV-Radiation for Systemic Use …
Matched Products: … Beta A 10000 Cap ... BETA-CAROTENE 15 MGPROVITAMIN A 25.000 IU …
Matched Iupac: … 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex …
Matched Description: … It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits. ... [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. ... [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS). …
Matched Mixtures name: … For-2 ... Vitamins A, C & E Cap. ... Eden With Vitamins A, C, and E …
Matched Categories: … Vitamin A ... Protectives Against UV-Radiation for Systemic Use …
Matched Products: … Beta A 10000 Cap ... BETA-CAROTENE 15 MGPROVITAMIN A 25.000 IU …
Darunavir
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido ... N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6 ... [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido ... ]-1-phenylbutan-2-yl]carbamate …
Matched Description: … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... for COVID-19, due to in vitro evidence supporting its ability to combat this infection. ... for the effective management of HIV-1 infection. …
Matched Salts cas: … 635728-49-3 ... 1447721-06-3 …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido ... ]-1-phenylbutan-2-yl]carbamate …
Matched Description: … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... for COVID-19, due to in vitro evidence supporting its ability to combat this infection. ... for the effective management of HIV-1 infection. …
Matched Salts cas: … 635728-49-3 ... 1447721-06-3 …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene ... (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2 ... (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene- …
Matched Iupac: … (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo ... [3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... Similar compounds include [meropenem], known for having greater activity against Gram negative bacteria ... Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... IMIPENEM E CILASTATINA SUN …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo ... [3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... Similar compounds include [meropenem], known for having greater activity against Gram negative bacteria ... Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... IMIPENEM E CILASTATINA SUN …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Saxagliptin
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Synonyms: … (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …
Matched Salts cas: … 945667-22-1 …
Matched Categories: … Drugs Used in Diabetes …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …
Matched Salts cas: … 945667-22-1 …
Matched Categories: … Drugs Used in Diabetes …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ERTAPENEM MEVON POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1G/VIAL ... Ertapenem for Injection …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ERTAPENEM MEVON POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1G/VIAL ... Ertapenem for Injection …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ... (CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA …
Matched Description: … in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group ... in alanine and lysine residues. ... It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Matched Description: … in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group ... in alanine and lysine residues. ... It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Clofarabine
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … Cl-F-Ara-A ... (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol ... 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic ... leukaemia (ALL), only after at least two other types of treatment have failed. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... OCT2 Substrates with a Narrow Therapeutic Index ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index …
Matched Products: … EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for Infusion ... Evoltra Concentrate Solution for Infusion 1mg/ml …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic ... leukaemia (ALL), only after at least two other types of treatment have failed. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... OCT2 Substrates with a Narrow Therapeutic Index ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index …
Matched Products: … EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for Infusion ... Evoltra Concentrate Solution for Infusion 1mg/ml …
Formoterol
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Synonyms: … N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide ... 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilide ... 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-α-methylphenethyl)amino]ethyl}formanilide …
Matched Iupac: … N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide …
Matched Description: … of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of ... first approved for use in the United States in 2001. ... action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever …
Matched Mixtures name: … BUDESONIDE E FORMOTEROLO SANDOZ ... BUDESONIDE E FORMOTEROLO SANDOZ ... BUDESONIDE E FORMOTEROLO SANDOZ …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases ... Selective Beta 2-adrenergic Agonists …
Matched Products: … FORADIL P + 3 INHALATOR ... FORADIL P + 3 INHALATOREN ... CYCLOCAPS FORMOTERO12UG+IN …
Matched Iupac: … N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide …
Matched Description: … of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of ... first approved for use in the United States in 2001. ... action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever …
Matched Mixtures name: … BUDESONIDE E FORMOTEROLO SANDOZ ... BUDESONIDE E FORMOTEROLO SANDOZ ... BUDESONIDE E FORMOTEROLO SANDOZ …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases ... Selective Beta 2-adrenergic Agonists …
Matched Products: … FORADIL P + 3 INHALATOR ... FORADIL P + 3 INHALATOREN ... CYCLOCAPS FORMOTERO12UG+IN …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … (+)-Cyanidan-3-ol …
Matched Iupac: … (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Slim 2 …
Matched Iupac: … (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Slim 2 …
Ergosterol
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Iupac: … (1R,3aR,7S,9aR,9bS,11aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H ... ,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol …
Matched Description: … A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably ... AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in …
Matched Description: … A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably ... AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in …
Tapentadol
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596]
Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited ... Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited ... Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. …
Esmolol
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester ... (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Description: … The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol ... It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Other esmolol formulations are still available for use.[L43942] …
Matched Salts cas: … 81161-17-3 …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Description: … The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol ... It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Other esmolol formulations are still available for use.[L43942] …
Matched Salts cas: … 81161-17-3 …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …
Enmetazobactam
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept ... -2-carboxylate ... (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl ... }-3-methyl-1H-1,2,3-triazol-3-ium …
Matched Description: … Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. ... penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in ... combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl ... }-3-methyl-1H-1,2,3-triazol-3-ium …
Matched Description: … Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. ... penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in ... combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for …
Leuprolide
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched International brands: … Prostap 3 …
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol ... -4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido] ... -2-carboxamide ... -3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine …
Matched Description: … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for ... Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily ... responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced prostate …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE ... LUCRIN 3 MONTH DEPOT, 11.25MG SUSPENSION ... Leuprorelin Sandoz 5 mg - Implantat für 3 Monate …
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol ... -4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido] ... -2-carboxamide ... -3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine …
Matched Description: … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for ... Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily ... responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced prostate …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE ... LUCRIN 3 MONTH DEPOT, 11.25MG SUSPENSION ... Leuprorelin Sandoz 5 mg - Implantat für 3 Monate …
Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (UV, formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Gadobutrol
Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Synonyms: … gadolinium(III) 2,2',2''-(10-((2R,3S )-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7 …
Matched Iupac: … 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Matched Description: … agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast ... fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … GADOVIST 1.0 MMOL/ML SOLUTION FOR INJECTION ... Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …
Matched Iupac: … 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Matched Description: … agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast ... fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … GADOVIST 1.0 MMOL/ML SOLUTION FOR INJECTION ... Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of ... It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration ... Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor …
Matched Salts cas: … 1258291-80-3 …
Matched Mixtures name: … PERINDO/IN RAT T 5/1.25 ... PERINDO/IN RAT T 5/1.25 ... PERDAPAX 2 MG/0.625 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … HITEN 2 (Perindopril tert-Butylamine Tablets 2 mg) ... Mariper 2 mg Tabletten ... PADERO 2 MG TABLET, 30 ADET …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of ... It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration ... Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor …
Matched Salts cas: … 1258291-80-3 …
Matched Mixtures name: … PERINDO/IN RAT T 5/1.25 ... PERINDO/IN RAT T 5/1.25 ... PERDAPAX 2 MG/0.625 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … HITEN 2 (Perindopril tert-Butylamine Tablets 2 mg) ... Mariper 2 mg Tabletten ... PADERO 2 MG TABLET, 30 ADET …
Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Displaying drugs 1 - 25 of 15273 in total