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Displaying drugs 1 - 25 of 4718 in total
Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander or dry defatted cat pelt. It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. An allergic reaction to cats is induced by the presence of antigen-specific IgE...
Approved
Matched Synonyms: … Cat dander diagnostic allergen extract …
Matched Name: … Cat dander extract …
Matched Description: … Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander ... defatted cat pelt. It is used in the diagnosis and treatment (immunotherapy) of patients with a history ... clinical evaluation, and skin test reactivity. Cat dander extract can be used in immunotherapy in individuals …
Matched Mixtures name: … Standardized Cat Hair Allergenic Extract ... Standardized Cat Hair Allergenic Extract …
Matched Products: … Standardized Cat Hair Ap ... Standardized Cat Pelt …
CAT-213 is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Name: … CAT-213 …
Matched Description: … CAT-213 is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been brought to market.
Investigational
Matched Description: … TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been …
Experimental
Matched Synonyms: … caproyl-CoA ... caproyl-coenzyme A ... Hexanoyl-Coenzyme A
Matched Name: … Hexanoyl-CoA
Matched Categories: … Coenzyme A
Experimental
Matched Synonyms: … 3-Acetoacetyl-CoA ... Acetoacetyl coenzyme A ... Acetoacetyl-Coenzyme A
Matched Name: … Acetoacetyl-CoA
Felis catus skin or pelt is used in allergenic testing.
Approved
Matched Synonyms: … cat skin extract ... Standardized cat pelt …
Matched Mixtures name: … Standardized Cat Hair Allergenic Extract ... Standardized Cat Hair Allergenic Extract …
Matched Products: … Extract-standardized Cat Pelt ... Allergenic Extract, Standardized Cat Pelt ... Cat Pelt, Standardized …
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular...
Investigational
Nutraceutical
Matched Synonyms: … CoA ... CoA-SH …
Matched Name: … Coenzyme A
Matched Description: … coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as ... Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation ... as a substrate. In humans, CoA biosynthesis requires cysteamine, pantothenate, and adenosine triphosphate …
Experimental
Matched Synonyms: … propanoyl-coenzyme A ... Propionyl coenzyme A ... Propionyl-CoA
Matched Name: … Propanoyl-CoA
Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. Its use as a food...
Approved
Vet approved
Matched Description: … that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally ... food preservation and flavoring agent. Its use as a food additive is also approved in Europe. Sodium propionate …
A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]
Experimental
Matched Description: … attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem] ... A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities …
Experimental
Matched Name: … Myristoyl-Coa
Matched Categories: … Coenzyme A
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … compactin. Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity ... 000 times greater than the HMG-CoA substrate itself. Mevastatin is a pro-drug that is activated by in ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic ... cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to ... disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to "propranolol":http://www.drugbank.ca/drugs/DB00571.
Approved
Matched Description: … Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with ... activity. Its potency is similar to "propranolol":http://www.drugbank.ca/drugs/DB00571. …
Lovastatin is a cholesterol-lowering agent that belongs to the class of medications called statins. It was the second agent of this class discovered. It was discovered by Alfred Alberts and his team at Merck in 1978 after screening only 18 compounds over 2 weeks. The agent, also known as mevinolin,...
Approved
Investigational
Matched Synonyms: … (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-py …
Matched Description: … hydroxymethylglutarate (HMG), a substituent of HMG-Coenzyme A (HMG-CoA), a substrate of the cholesterol ... acid pathway. Lovastatin is a competitive inhibitor of HMG-CoA reductase with a binding affinity 20,000 times ... times greater than HMG-CoA. Lovastatin differs structurally from mevastatin by a single methyl group at …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Experimental
Matched Name: … 3r-Hydroxydecanoyl-Coa
On August 8, 2001 the U.S. Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal Rhabdomyolysis, a severe adverse reaction from this cholesterol-lowering (lipid-lowering) product. It has also been withdrawn from the Canadian market.
Approved
Withdrawn
Matched Description: … market, due to reports of fatal Rhabdomyolysis, a severe adverse reaction from this cholesterol-lowering …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Experimental
Matched Synonyms: … 4-hydroxybenzoyl CoA ... 4-Hydroxybenzoyl-CoA ... 4-Hydroxybenzoyl-coenzyme A
Matched Name: … 4-Hydroxybenzoyl Coenzyme A
Matched Categories: … Coenzyme A
Experimental
Matched Name: … (S)-Hmg-Coa
Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of...
Approved
Matched Synonyms: … 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl …
Matched Description: … terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl ... Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus ... (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Experimental
Matched Name: … 3-Hydroxybutyryl-Coenzyme A
Matched Categories: … Coenzyme A
Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reducuase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Approved
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reducuase catalyzes the conversion of HMG-CoA to mevalonic ... cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Barium sulfate is an inorganic compound with the chemical formula BaSO4. Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield. This drug is used as a contrast agent in diagnostic x-ray...
Approved
Matched Description: … heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic …
Matched Products: … E-Z-Cat Dry ... Readi-Cat 2 ... Readi-Cat 2 Banana Smoothie …
Pravastatin is a cholesterol-lowering agent that belongs to a class of medications known as statins. It was derived from microbial transformation of mevastatin, the first statin discovered. It is a ring-opened dihydroxyacid with a 6’-hydroxyl group that does not require in vivo activation. Pravastatin is one of the lower potency...
Approved
Matched Synonyms: … 8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid …
Matched Description: … Pravastatin is a cholesterol-lowering agent that belongs to a class of medications known as statins. ... the first statin discovered. It is a ring-opened dihydroxyacid with a 6’-hydroxyl group that does not require ... cells, increased selectivity for hepatic tissues, and a reduction in side effects compared with lovastatin …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Displaying drugs 1 - 25 of 4718 in total