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Displaying all 7 drugs
PX-478
PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer
and small cell lung cancer that express HIF-1 alpha.
Investigational
Matched Name: … PX-478 …
Matched Description: … PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical ... PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express …
Matched Description: … PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical ... PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express …
PX-102
PX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study With Px-102).
Investigational
Matched Name: … PX-102 …
Matched Description: … With Px-102). ... PX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study …
Matched Description: … With Px-102). ... PX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study …
PXT 3003
PXT 3003 is in phase 3 clinical trials for the treatment of Charcot-Marie-Tooth disease type 1A in adults.
Investigational
Matched Name: … PXT 3003 …
Matched Description: … PXT 3003 is in phase 3 clinical trials for the treatment of Charcot-Marie-Tooth disease type 1A in adults …
Matched Description: … PXT 3003 is in phase 3 clinical trials for the treatment of Charcot-Marie-Tooth disease type 1A in adults …
PXL-770 free acid anhydrous
Investigational
Matched Synonyms: … PXL770 free acid anhydrous ... PXL 770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Matched Salts name: … PXL-770 …
Matched Name: … PXL-770 free acid anhydrous …
Matched Salts name: … PXL-770 …
PX-12
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Name: … PX-12 …
Matched Description: … Initial trials correlated doses of Px-12 with increased patient survival. ... PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), ... Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated …
Matched Description: … Initial trials correlated doses of Px-12 with increased patient survival. ... PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), ... Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated …
Pentazocine
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Approved
Vet approved
Matched International brands: … Talwin PX …
Displaying all 7 drugs