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Displaying drugs 1 - 25 of 10287 in total

Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen

Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …

Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen

Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate …
Matched Name: … Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen …

Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen

Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …

Elapegademase

Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN …
Matched Description: … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group …
Matched Categories: … Pegylated agents ... Antineoplastic and Immunomodulating Agents …

Imiquimod

Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Description: … Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. …
Matched Categories: … Antineoplastic Agents ... Immunomodulatory Agents ... Immunosuppressive Agents ... Skin and Mucous Membrane Agents …
Matched Products: … Truemed Group LLC …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Description: … Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. …
Matched Categories: … Autonomic Agents ... Central Nervous System Agents ... Gastrointestinal Agents ... Neurotransmitter Agents ... Peripheral Nervous System Agents …
Matched Products: … Truemed Group LLC …

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast agents …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Categories: … Antidepressive Agents ... Antidepressive Agents Indicated for Depression ... Serotonin Agents ... Agents that produce hypertension ... Neurotransmitter Agents …

Gilteritinib

Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Description: … This drug was approved after being designed as an orphan drug with a fast track and priority review status ... from this group. ... tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents …
Matched Categories: … Antineoplastic Agents ... QTc Prolonging Agents ... Moderate Risk QTc-Prolonging Agents ... Antineoplastic and Immunomodulating Agents …

Beroctocog alfa

Approved
Investigational
Matched Categories: … Hematologic Agents …
Matched Products: … Truemed Group LLC …

Sevoflurane

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Description: … [L42340] Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved ... Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. …
Matched Categories: … Hypotensive Agents ... QTc Prolonging Agents ... Agents that produce hypertension ... Central Nervous System Agents ... Potential QTc-Prolonging Agents …
Matched Products: … Truemed Group LLC …

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … [A229108] Oxytocin continues to be an important tool in modern obstetrics to induce labor when indicated ... [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear …
Matched Categories: … Uterotonic agents ... QTc Prolonging Agents ... Reproductive Control Agents ... Potential QTc-Prolonging Agents …
Matched Products: … Truemed Group LLC …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic Agents, Alkylating ... Cardiotoxic antineoplastic agents …

Cedazuridine

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias ... A215117, A215127, L14897] Cedazuridine was first reported in 2014,[A215107] and was subsequently approved ... [A215082, A215092, A215097] Hypomethylating agents such as [decitabine] and [azacitidine] are used to …

Lorpiprazole

Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder. It is a piperazinyl-triazole derivative.
Approved
Matched Categories: … Antidepressive Agents ... Serotonin Agents …

Sunitinib

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Description: … For these purposes, sunitinib is generally available as an orally administered formulation. ... On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal …
Matched Categories: … Antineoplastic Agents ... Hepatotoxic Agents ... Angiogenesis Modulating Agents ... QTc Prolonging Agents ... Blood Glucose Lowering Agents …

Nabilone

Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Description: … It is also approved for use in treatment of anorexia and weight loss in patients with AIDS. ... Nabilone is approved by the FDA for the treatment of nausea and vomiting associated with cancer chemotherapy ... Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006 …
Matched Categories: … Autonomic Agents ... Agents producing tachycardia ... Hypotensive Agents ... Tranquilizing Agents ... Gastrointestinal Agents …

Phylloquinone

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Description: … [L33319] Phylloquinone has been synthesized since at least 1939,[A234384] and was approved by the …
Matched Categories: … Hematologic Agents ... Fibrin Modulating Agents …
Matched Products: … Truemed Group LLC …

Flunitrazepam

Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Approved
Illicit
Matched Categories: … Anti-Anxiety Agents ... GABA Agents ... Tranquilizing Agents ... Neurotransmitter Agents ... Central Nervous System Agents …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … [L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. ... [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive …
Matched Categories: … Sensory System Agents ... Central Nervous System Agents ... Peripheral Nervous System Agents …

Pidolic acid

Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Description: … pidolic acid as an active ingredient for any particular formal indication. ... There are currently little to no medicines available that are clinically approved or marketed for employing …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Categories: … Approved Treatments for COVID-19 ... Antiviral Agents ... Anti-Infective Agents …

Methyltestosterone

A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Categories: … Anabolic Agents ... Antineoplastic Agents ... Antineoplastic Agents, Hormonal …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … Flupentixol is an antipsychotic drug of the thioxanthene group. ... It is approved for use in Canada and other countries around the world, but not in the US. ... [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors. …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents ... Serotonin Agents …

Colloidal oatmeal

Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor …
Matched Products: … An Adc Whitening Essence ... An Adc Face Up Special Program …
Displaying drugs 1 - 25 of 10287 in total