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Displaying drugs 1 - 25 of 5154 in total
An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. This new concept of oncological immunotherapy consists of an attempt to trigger the immune system of the host...
Investigational
Matched Description: … developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be ... create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber …
The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl...
Approved
Investigational
Matched Description: … The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced ... increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as ... other products whose form is as ethyl esters. It is a complex mixture of the free fatty acids form containing …
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Description: … Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125. …
Matched Categories: … CA-125 Antigen …
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered...
Approved
Matched Synonyms: … 6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid ... ((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... methylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure …
Matched Description: … Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and ... it is administered in combination with cilastatin, a renal dipeptidase inhibitor. [PubChem] …
Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a...
Approved
Matched Description: … anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition ... Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic ... Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible …
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Description: … FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in ... kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. …
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … 2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}- …
Matched Description: … Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat ... by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into ... effective against genotypes 1a, 1b, 4a, and 5a and with a lesser activity against genotypes 2a and 3a of HCV …
A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
Approved
Experimental
Matched Description: … A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine. [PubChem]
Approved
Investigational
Matched Synonyms: … 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-Bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been …
Ubidecarenone, also known as coenzyme Q10, is a 1,4-benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail.It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation.The ubidecarenone is the coenzyme destined for mitochondrial...
Approved
Investigational
Nutraceutical
Matched Description: … chemical subunits in its tail.[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in ... fundamental for cells that have a high metabolic demand.[L1062] Ubidecarenone is sold as a dietary supplement and ... Ubidecarenone, also known as coenzyme Q10, is a 1,4-benzoquinone, where Q refers to the quinone chemical …
Matched Mixtures name: … Co-q10 and Vitamin E …
Matched Products: … Biomed Co Q 10 ... Co Q 10 - 50mg Cap ... Co-enzyme Q-10 …
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide is a solid. This compound belongs to the penicillins. These are organic compounds containing the penicillin core structure, which is structurally characterized by a penam ring bearing two methyl groups at position 2, and an amide group at position 6 [starting from the sulfur atom at position 1]. This...
Experimental
Matched Name: … N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide …
Matched Description: … 3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide is a solid. This compound belongs to the ... structure, which is structurally characterized by a penam ring bearing two methyl groups at position 2 …
Dorzolamide is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension.
Approved
Matched Description: … Dorzolamide is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower …
Biapenem has been used in trials studying the treatment of Bacterial Infections.
Investigational
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Synonyms: … CO
Matched Description: … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than ... biological/homeostatic functions [L2529]. Carbon monoxide (CO), is a ubiquitous environmental product of organic combustion ... [A32758]. Exhaled CO (eCO), similar to exhaled nitric oxide (eNO), has been evaluated as a candidate breath …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Co-HE-O2-N2 Mixture ... Lung Diffusion Test Mix No Ne Co
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
Approved
Investigational
Matched Synonyms: … )-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... [((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid …
Matched Description: … A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, …
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic ... formation of DHF and THF. This results in a deficiency of coenzymes and a resultant buildup of toxic substances ... bypass DHFR reduction and act as a cellular replacement for the co-factor THF, thereby preventing these …
Matched Products: … Leucovorin Ca Inj (pharm. Bulk Vial) 10mg/ml …
RP101 is targeted at preventing tumor cells from developing resistance to chemotherapy, one of the most challenging areas facing oncologists. RP101 would be used as a co-treatment with cytostatic drugs to give a broader range of chemotherapy treatment options, thereby extending survival periods and improving quality of life for the...
Investigational
Matched Description: … oncologists. RP101 would be used as a co-treatment with cytostatic drugs to give a broader range of chemotherapy …
Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts its effect by increasing calcium sensitivity of myocytes by binding to cardiac troponin C...
Investigational
Matched Description: … binding to cardiac troponin C in a calcium-dependent manner. It also has a vasodilatory effect, by opening ... Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart ... calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts …
A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
Experimental
Matched Description: … A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is ... is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] …
Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. It displays a reddish-orange light,...
Approved
Investigational
Matched Description: … Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is ... in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion test. Other ... element in the universe by mass but a rare element on Earth. It displays a reddish-orange light, and is commonly …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Lung Diffusion Test Mix No Ne Co
Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Matched Description: … Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated ... (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph …
A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Experimental
Matched Synonyms: … Co-galactoisomerase ... Co-waldenase …
Matched Description: … A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized ... as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids …
PBI-1402 is a small molecule synthetic compound with oral Bioavailability. The compound activates neutrophils, enhancing their survival and activation with comparable efficacy to GM-CSF, G-CSF and EPO, which are currently used to treat anemia. However, it has been shown that when co-administered with these compounds, effects are additive, making PBI-1402...
Investigational
Matched Description: … properties are not known. PBI-1402 has a dual therapeutic action; as a chemoprotectant and hematopoietic progenitor ... PBI-1402 is a small molecule synthetic compound with oral Bioavailability. The compound activates neutrophils ... treat anemia. However, it has been shown that when co-administered with these compounds, effects are additive …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Desglucolanatoside A
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. It is also known by the brand name of Xalatan manufactured by...
Approved
Investigational
Matched Synonyms: … 5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate …
Matched Description: … Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the …
Displaying drugs 1 - 25 of 5154 in total