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Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a...
Approved
Matched Description: … anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition ... Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic ... Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible …
Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. It displays a reddish-orange light,...
Approved
Investigational
Matched Description: … Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is ... element in the universe by mass but a rare element on Earth. It displays a reddish-orange light, and is commonly …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Lung Diffusion Test Mix No Ne Co
An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. This new concept of oncological immunotherapy consists of an attempt to trigger the immune system of the host...
Investigational
Matched Description: … developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be ... create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber …
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered...
Approved
Matched Synonyms: … 6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid ... ((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... methylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure …
Matched Description: … Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and ... it is administered in combination with cilastatin, a renal dipeptidase inhibitor. [PubChem] …
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Description: … Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125. …
Matched Categories: … CA-125 Antigen …
Dorzolamide is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension.
Approved
Matched Description: … Dorzolamide is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower …
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … 2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}- …
Matched Description: … Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat ... by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into ... effective against genotypes 1a, 1b, 4a, and 5a and with a lesser activity against genotypes 2a and 3a of HCV …
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide is a solid. This compound belongs to the penicillins. These are organic compounds containing the penicillin core structure, which is structurally characterized by a penam ring bearing two methyl groups at position 2, and an amide group at position 6 [starting from the sulfur atom at position 1]. This...
Experimental
Matched Name: … N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide …
Matched Description: … 3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide is a solid. This compound belongs to the ... structure, which is structurally characterized by a penam ring bearing two methyl groups at position 2 …
Ergoloid mesylate is a dihydrogenated ergot (Claviceps purpurea) derivative alkaloid used as a vasodilator agent. Ergoloid Mesylate is the only vasodilator that has shown mild benefits in the treatment of vascular dementia. Ergoloid Mesylate is a mixture of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. It has been proposed to...
Approved
Matched Synonyms: … co-dergocrine mesilate ... co-dergocrine mesylate ... co-dergocrine methanesulfonate …
Matched Description: … Ergoloid mesylate is a dihydrogenated ergot (Claviceps purpurea) derivative alkaloid used as a vasodilator agent ... treatment of vascular dementia. Ergoloid Mesylate is a mixture of three different ergotamantriones: dihydroergocornine ... and dihydroergocryptine. It has been proposed to be a neuroprotective agent. The mechanism of its therapeutic …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine. [PubChem]
Approved
Investigational
Matched Synonyms: … 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-Bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been …
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air. It is toxic to hemoglobic animals (including humans) when encountered in concentrations above about 35 ppm, although it is also produced in normal animal metabolism in low quantities, and is thought to have...
Approved
Investigational
Matched Synonyms: … CO
Matched Description: … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Co-HE-O2-N2 Mixture ... Lung Diffusion Test Mix No Ne Co
Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression ... Targeting CDK4/6 with enhanced precision may play a role in ensuring that cancer cells do not continue …
Matched Mixtures name: … Kisqali Femara Co-pack ... Kisqali Femara Co-pack ... Kisqali Femara Co-pack …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Desglucolanatoside A
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Ubidecarenone, also known as coenzyme Q10, is a 1,4-benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail.[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation.[A31413] The ubidecarenone is the coenzyme destined...
Approved
Investigational
Nutraceutical
Matched Description: … chemical subunits in its tail.[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in ... fundamental for cells that have a high metabolic demand.[L1062] Ubidecarenone is sold as a dietary supplement and ... Ubidecarenone, also known as coenzyme Q10, is a 1,4-benzoquinone, where Q refers to the quinone chemical …
Matched Mixtures name: … Co-q10 and Vitamin E …
Matched Products: … Biomed Co Q 10 ... Co Q 10 - 50mg Cap ... Co-enzyme Q-10 …
A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
Experimental
Matched Description: … A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is ... is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] …
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … hemophilia A with factor VIII inhibitors.[A31279, L1016] It was created by Chugai Pharmaceuticals Co. Ltd. ... Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation ... and co-developed with Roche and Genentech.[L1015] …
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. [PubChem]
Approved
Investigational
Matched Synonyms: … )-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... [((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid …
Matched Description: … A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, …
An anthelmintic used in most schistosome and many cestode infestations.
Approved
Investigational
Vet approved
An anthelmintic used in most schistosome and many cestode infestations.
Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts its effect by increasing calcium sensitivity of myocytes by binding to cardiac troponin C...
Approved
Investigational
Matched Description: … binding to cardiac troponin C in a calcium-dependent manner. It also has a vasodilatory effect, by opening ... Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart ... calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts …
Biapenem has been used in trials studying the treatment of Bacterial Infections.
Investigational
Biapenem has been used in trials studying the treatment of Bacterial Infections.
Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. It is also known by the brand name of Xalatan manufactured by...
Approved
Investigational
Matched Synonyms: … 5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate …
Matched Description: … Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma ... hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the …
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug...
Approved
Investigational
Vet approved
Matched Description: … with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent …
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Approved
Investigational
Vet approved
An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. [PubChem]
Nitrogen is a chemical element with symbol N and atomic number 7. At room temperature, it is a transparent, odorless diatomic gas. Liquid nitrogen is used principally in cryotherapy for removal of diseased skin. Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and...
Approved
Vet approved
Matched Description: … Nitrogen is a chemical element with symbol N and atomic number 7. At room temperature, it is a transparent …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Co-HE-O2-N2 Mixture ... Lung Diffusion Test Mix No Ne Co
Matched Products: … Nitrogen c70f6047-a0cb-4f70-aa3a-78acd681efc3 …
A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Experimental
Matched Synonyms: … Co-galactoisomerase ... Co-waldenase …
Matched Description: … A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized ... as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids …
Displaying drugs 1 - 25 of 4517 in total