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Displaying drugs 1 - 25 of 6624 in total
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Approved
Investigational
Matched Synonyms: … Cholest-5-en-3beta-ol ... (3β,14β,17α)-cholest-5-en-3-ol
Matched Iupac: … -methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 3-(β-chlorovinyl)-1-pentyn-3-ol ... 3-(beta-chlorovinyl)-1-pentyn-3-ol
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
Matched Description: … It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance …
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Synonyms: … (22E,24S)-24-methylcholesta-5,7,22-trien-3β-ol
Matched Iupac: … 3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched International brands: … Children's Ibuprofen
Matched Synonyms: … (±)-ibuprofen ... Ibuprofen ... (RS)-ibuprofen
Matched Name: … Ibuprofen
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... was in 1960 while researching for a safer alternative for aspirin. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Acetaminophen and Ibuprofen ... Acetaminophen and Ibuprofen ... Acetaminophen and Ibuprofen
Matched Salts name: … Ibuprofen lysine ... Ibuprofen aluminum ... Ibuprofen arginine ... Ibuprofen sodium ... Ibuprofen potassium …
Matched Categories: … Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … Help I Have an Aching Body ... Ibuprofen ... Ibuprofen Junior …
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol ... 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol ... 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Matched Description: … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. …
Matched Categories: … Beta Blocking Agents, Non-Selective …
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker …
Matched Categories: … Beta Blocking Agents, Non-Selective …
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Synonyms: … 17α-methyl-Δ4-androsten-17β-ol-3-one ... 17alpha-Methyl-3-oxo-4-androsten-17beta-ol ... 4-Androstene-17alpha-methyl-17beta-ol-3-one …
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Synonyms: … (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
Matched Iupac: … dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
Matched Description: … Ergocalciferol is an inactivated vitamin D analog. …
Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products. Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Synonyms: … (2E)-3-phenylprop-2-en-1-ol
Matched Iupac: … (2E)-3-phenylprop-2-en-1-ol
Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Synonyms: … (3R)-1-((1R,2R)-2-(2-(3,4-dimethoxyphenyl)ethoxy)cyclohexyl)pyrrolidin-3-ol
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol
Matched Description: … It is an investigational drug under regulatory review by FDA. ... Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion ... It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates …
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol
Matched Description: … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required …
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol ... (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
Matched Iupac: … 7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
Matched Description: … ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Synonyms: … 2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … (+)-Cyanidan-3-ol
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Synonyms: … 26-(Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
Matched Iupac: … 26-(4-nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
Matched Description: … Spermicides are locally acting non-hormonal contraceptives. ... N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and …
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
Matched Description: … Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Description: … that may be combined with [acetaminophen] or [ibuprofen]. ... [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose ... Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an
Matched Mixtures name: … Ibuprofen+methocarbamol Caplets ... Muscle & Back Pain Relief With Ibuprofen ... Acetaminophen 325mg + Methocarbamol 400mg Caplets …
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … [L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide …
Matched Mixtures name: … Acetaminophen Aspirin Caffeine ... Acetaminophen Aspirin Caffeine ... Acetaminophen, Aspirin, Caffeine …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Cold Formula Daytime Nighttime, Non-Aspirin, Multi-Symptom ... Cold Formula Daytime Nighttime, Non-Aspirin, Multi-Symptom ... Aspirin Free Cold Head Congestion Day Time …
Matched Products: … Decongestant PE Non Drowsy ... Physicians Care Non-Drowsy Sinus ... Nasal Decongestant Non-Drowsy …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … for an extended period. ... [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as ... an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics …
Matched Mixtures name: … Oxycodone Hydrochloride and Ibuprofen ... Oxycodone Hydrochloride and Ibuprofen ... Oxycodone hydrochloride and Ibuprofen
Matched Categories: … oxycodone and ibuprofen
Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Synonyms: … 6α-Methyl-4-pregnene-3,20-dion-17α-ol acetate …
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Synonyms: … 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol
Displaying drugs 1 - 25 of 6624 in total