The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,683 drug entries including 2,627 approved small molecule drugs, 1,117 approved biotech (protein/peptide) drugs, 128 nutraceuticals and over 5,505 experimental drugs. Additionally, 5,130 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
- AcetaminophenFor temporary relief of fever, minor aches, and pains.
- Acetylsalicylic acidFor use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and...
- SalbutamolFor symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, and other chronic bronchopulmonary disorders such as COPD.
- MetforminFor use as an adjunct to diet and exercise in adult patients (18 years and older) with non-insulin dependent diabetes mellitus. Metformin may also be used for the management of...
- MorphineFor the relief and treatment of severe pain.
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.
Cannabinoids in Epilepsy: A New Era of Treatments
From Discovery to Resistance to Progress
Ketamine: the key to treatment resistant depression?
Tideglusib: From Alzheimer's to Caries Lesion Natural Repair
CFTR Modulators Helping CF Patients Catch Their Breath
New Antivirals Provide Hope for Eradication of Hepatitis C – If You Can Afford It
DrugBank is offered to the public as a freely available resource.
Use and re-distribution of the data, in whole or in part, for commercial purposes (including internal use) requires a license. We ask that users who download significant portions of the database cite the DrugBank paper in any resulting publications.