Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3.
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Hammani K, Henriet P, Silbiger SM, DeClerck YA
Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3.
Gene. 1996 May 8;170(2):287-8.
- PubMed ID
- 8666262 [ View in PubMed]
- Abstract
Using a cDNA probe, two genomic clones were obtained encoding the human tissue inhibitor of metalloproteinases-3 (TIMP-3). Analysis of these clones showed that they contained four distal exons and three introns of the gene. Although the intron-exon structure is similar to that of the timp1 gene, the first intron of the timp3 gene is much longer, being at least 17.5 kb in size.