Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene.
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Valle F, Gosset G, Tenorio B, Oliver G, Bolivar F
Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene.
Gene. 1986;50(1-3):119-22.
- PubMed ID
- 3556321 [ View in PubMed]
- Abstract
Penicillin acylase is utilized in the enzymatic production of semisynthetic penicillins. The enzyme is composed of two different subunits that originate from a common precursor. The partial nucleotide (nt) sequence of the structural gene has been published. This paper reports the nt sequence of the regulatory region of this gene, the identification of a functional promoter, the transcriptional start point, and the description of possible regulatory regions.