Chemoprevention of severe neonatal hyperbilirubinemia.
Article Details
- CitationCopy to clipboard
Drummond GS, Kappas A
Chemoprevention of severe neonatal hyperbilirubinemia.
Semin Perinatol. 2004 Oct;28(5):365-8.
- PubMed ID
- 15686268 [ View in PubMed]
- Abstract
The uses of synthetic heme analogues that are competitive inhibitors of heme oxygenase, the rate-limiting enzyme in the production of bilirubin, represent a novel means of controlling severe hyperbilirubinemia in the newborn. The logic of this approach and the use of stannsoporfin (tin mesoporphyrin) as the compound of choice are discussed.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Stannsoporfin Heme oxygenase 1 Protein Humans UnknownNot Available Details Stannsoporfin Heme oxygenase 2 Protein Humans UnknownNot Available Details