Enrofloxacin hydro-chloride dihydrate.

Article Details

Citation
Copy to clipboard

Miranda-Calderon JE, Gutierrez L, Flores-Alamo M, Garcia-Gutierrez P, Sumano H

Enrofloxacin hydro-chloride dihydrate.

Acta Crystallogr Sect E Struct Rep Online. 2014 Mar 26;70(Pt 4):o468-9. doi: 10.1107/S1600536814006059. eCollection 2014 Apr 1.

PubMed ID
24826167 [ View in PubMed
]
Abstract

The asymmetric unit of the title compound, C19H23FN3O3 (+).Cl(-).2H2O [systematic name: 4-(3-carb-oxy-1-cyclo-propyl-6-fluoro-4-oxo-1,4-di-hydro-quin-o-lin-7-yl)-1-ethyl -piperazin-1-ium chloride dihydrate], consists of two independent monocations of the protonated enrofloxacin, two chloride anions and four water mol-ecules. In the cations, the piperazinium rings adopt chair conformations and the dihedral angles between the cyclo-propyl ring and the 10-membered quinoline ring system are 56.55 (2) and 51.11 (2) degrees . An intra-molecular O-Hcdots, three dots, centeredO hydrogen bond is observed in each cation. In the crystal, the components are connected via O-Hcdots, three dots, centeredCl, N-Hcdots, three dots, centeredCl and O-Hcdots, three dots, centeredO hydrogen bonds, and a pi-pi inter-action between the benzene rings [centroid-centroid distance = 3.6726 (13) A], resulting in a three-dimensional array.

DrugBank Data that Cites this Article

Drugs