Characterization and localization to human chromosome 1 of human fast-twitch skeletal muscle calsequestrin gene.
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Fujii J, Willard HF, MacLennan DH
Characterization and localization to human chromosome 1 of human fast-twitch skeletal muscle calsequestrin gene.
Somat Cell Mol Genet. 1990 Mar;16(2):185-9.
- PubMed ID
- 2321095 [ View in PubMed]
- Abstract
A genomic clone encoding human fast-twitch skeletal muscle calsequestrin was isolated, and the amino acid sequence of the protein and the exon-intron boundaries of the gene were deduced from its sequence. A comparison with the rabbit gene showed that the sequence Glu-Asp-Asp-Asp-Asp near the COOH terminus of the rabbit sequence is lacking in the human gene. The calsequestrin gene was assigned to human chromosome 1 through the use of a human-mouse somatic cell hybrid mapping panel.