The role of gonadotropins in ovulation induction.

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Olive DL

The role of gonadotropins in ovulation induction.

Am J Obstet Gynecol. 1995 Feb;172(2 Pt 2):759-65.

PubMed ID
7872378 [ View in PubMed
]
Abstract

Currently two types of gonadotropin preparations are commercially available for ovulation induction: menotropins and follicle-stimulating hormone (FSH). Proper use of these agents is directed by many factors. Concern about the FSH-luteinizing hormone ratio and the bioconsistency of the preparations suggests the use of FSH in most situations. Regimens based on short-term incremental increases in gonadotropin dose (based on frequent sonographic and biochemical monitoring) seem to produce the highest pregnancy rates. Individualization of the patient's ovulation induction course on the basis of history of medication use and the reasons for ovulation induction therapy are also essential to optimize outcomes.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
MenotropinsFollicle-stimulating hormone receptorProteinHumans
Yes
Binder
Details
MenotropinsLutropin-choriogonadotropic hormone receptorProteinHumans
Yes
Not AvailableDetails