Muscarinic Antagonists
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Naji A, Gatling JW
Muscarinic Antagonists
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- PubMed ID
- 32491473 [ View in PubMed]
- Abstract
Muscarinic receptor antagonists (MRAs) are a group of agents that function by competitively blocking the cholinergic response manifested by acetylcholine (ACh) binding muscarinic receptors on exocrine glandular cells, cardiac muscle cells, and smooth muscle cells. Therefore, MRAs are heavily involved with the parasympathetic nervous system and act on different types of muscarinic receptors resulting in a wide array of clinical indications.
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