Vaccines for Pseudomonas aeruginosa: a long and winding road.

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Priebe GP, Goldberg JB

Vaccines for Pseudomonas aeruginosa: a long and winding road.

Expert Rev Vaccines. 2014 Apr;13(4):507-19. doi: 10.1586/14760584.2014.890053. Epub 2014 Feb 27.

PubMed ID
24575895 [ View in PubMed
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Abstract

Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no vaccine against this bacteria has come to market. This review describes the current state-of-the-art in vaccinology for this bacterium. This includes a discussion of those at risk for infection, the types of vaccines and the approaches for empirical and targeted antigen selection under development, as well as a perspective on where the field should go. In addition, the challenges in developing a vaccine for those individuals at risk are discussed.

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