Irinotecan.

Article Details

Citation
Copy to clipboard

Reyhanoglu G, Smith T

Irinotecan.

.

PubMed ID
32119328 [ View in PubMed
]
Abstract

Irinotecan is a medication used to manage and treat a variety of solid tumors. It is in the DNA topoisomerase I inhibitor class of drugs. Also known as CPT-11, irinotecan is used adjunctively with other therapeutic agents against colorectal cancer as a first- or second-line treatment. This activity reviews the indications, action, and contraindications for irinotecan as a valuable agent in treating solid tumors such as colorectal, pancreatic, ovarian, and lung cancers. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for healthcare team members in the care of patients who receive treatment with this medication.

DrugBank Data that Cites this Article

Drugs