Isochroman-6-carboxamides as highly selective 5-HT1D agonists: potential new treatment for migraine without cardiovascular side effects.
Article Details
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Ennis MD, Ghazal NB, Hoffman RL, Smith MW, Schlachter SK, Lawson CF, Im WB, Pregenzer JF, Svensson KA, Lewis RA, Hall ED, Sutter DM, Harris LT, McCall RB
Isochroman-6-carboxamides as highly selective 5-HT1D agonists: potential new treatment for migraine without cardiovascular side effects.
J Med Chem. 1998 Jun 18;41(13):2180-3.
- PubMed ID
- 9632349 [ View in PubMed]
- Abstract
Not Available
DrugBank Data that Cites this Article
- Binding Properties
Drug Target Property Measurement pH Temperature (°C) Sumatriptan 5-hydroxytryptamine receptor 1A Ki (nM) 341 N/A N/A Details Sumatriptan 5-hydroxytryptamine receptor 1B Ki (nM) 6.4 N/A N/A Details Sumatriptan 5-hydroxytryptamine receptor 1D Ki (nM) 2 N/A N/A Details