9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
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Narayanan SR, Keller BT, Borcherding DR, Scholtz SA, Borchardt RT
9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
J Med Chem. 1988 Mar;31(3):500-3.
- PubMed ID
- 3346868 [ View in PubMed]
- Abstract
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- Binding Properties
Drug Target Property Measurement pH Temperature (°C) (1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine Adenosylhomocysteinase Ki (nM) 41 N/A N/A Details