Generation of dendritic cell-based vaccines for cancer therapy.

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Reinhard G, Marten A, Kiske SM, Feil F, Bieber T, Schmidt-Wolf IG

Generation of dendritic cell-based vaccines for cancer therapy.

Br J Cancer. 2002 May 20;86(10):1529-33.

PubMed ID
12085199 [ View in PubMed
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Abstract

Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence the phenotypical and functional properties of dendritic cells and thereby the consecutive immune response mainly executed by T cells. Here we discuss various conditions, which are important during generation and administration of dendritic cells to elicit a tumouricidal T cell-based immune response.

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