Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene.
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Rosnet O, Mattei MG, Marchetto S, Birnbaum D
Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene.
Genomics. 1991 Feb;9(2):380-5.
- PubMed ID
- 2004790 [ View in PubMed]
- Abstract
We have isolated and sequenced part of a new gene of the tyrosine kinase family. This gene, called FLT3, has strong sequence similarities with members of a group of genes encoding growth factor receptors: FMS, KIT, and PDGFR. We have localized the human FLT3 gene to chromosome 13, band q12, and its mouse homolog to chromosome 5, region G.