Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines.
Article Details
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Ingman M, Gyllensten U
Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines.
Genome Res. 2003 Jul;13(7):1600-6.
- PubMed ID
- 12840039 [ View in PubMed]
- Abstract
To study the evolutionary history of the Australian and New Guinean indigenous peoples, we analyzed 101 complete mitochondrial genomes including populations from Australia and New Guinea as well as from Africa, India, Europe, Asia, Melanesia, and Polynesia. The genetic diversity of the Australian mitochondrial sequences is remarkably high and is similar to that found across Asia. This is in contrast to the pattern seen in previously described Y-chromosome data where an Australia-specific haplotype was found at high frequency. The mitochondrial genome data indicate that Australia was colonized between 40 and 70 thousand years ago, either by a single migration from a heterogeneous source population or by multiple movements of smaller groups occurring over a period of time. Some Australian and New Guinea sequences form clades, suggesting the possibility of a joint colonization and/or admixture between the two regions.
DrugBank Data that Cites this Article
- Polypeptides
Name UniProt ID NADH-ubiquinone oxidoreductase chain 3 P03897 Details NADH-ubiquinone oxidoreductase chain 4L P03901 Details Cytochrome c oxidase subunit 1 P00395 Details NADH-ubiquinone oxidoreductase chain 6 P03923 Details NADH-ubiquinone oxidoreductase chain 1 P03886 Details NADH-ubiquinone oxidoreductase chain 4 P03905 Details NADH-ubiquinone oxidoreductase chain 5 P03915 Details NADH-ubiquinone oxidoreductase chain 2 P03891 Details Cytochrome c oxidase subunit 2 P00403 Details ATP synthase subunit a P00846 Details