The three-dimensional structure of retinol-binding protein.
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Newcomer ME, Jones TA, Aqvist J, Sundelin J, Eriksson U, Rask L, Peterson PA
The three-dimensional structure of retinol-binding protein.
EMBO J. 1984 Jul;3(7):1451-4.
- PubMed ID
- 6540172 [ View in PubMed]
- Abstract
The complex of retinol with its carrier protein, retinol-binding protein (RBP) has been crystallized and its three-dimensional structure determined using X-ray crystallography. Its most striking feature is an eight-stranded up-and-down beta barrel core that completely encapsulates the retinol molecule. The retinol molecule lies along the axis of the barrel with the beta-ionone ring innermost and the tip of the isoprene tail close to the surface.