Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.
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Hentze MW, Keim S, Papadopoulos P, O'Brien S, Modi W, Drysdale J, Leonard WJ, Harford JB, Klausner RD
Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.
Proc Natl Acad Sci U S A. 1986 Oct;83(19):7226-30.
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- 3020541 [ View in PubMed]
- Abstract
A genomic phage clone containing a full-length copy of a functional human gene for ferritin heavy chain has been isolated. The gene consists of four exons spanning approximately 3 kilobases and has been localized to chromosome 11. The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of murine fibroblasts actively transcribe human ferritin heavy-chain mRNA.