Nucleotide sequence coding for the flavoprotein subunit of the fumarate reductase of Escherichia coli.
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Cole ST
Nucleotide sequence coding for the flavoprotein subunit of the fumarate reductase of Escherichia coli.
Eur J Biochem. 1982 Mar 1;122(3):479-84.
- PubMed ID
- 7037404 [ View in PubMed]
- Abstract
The nucleotide sequence of the frdA gene, which encodes the flavoprotein subunit of the fumarate reductase, of Escherichia coli, has been determined. A polypeptide of Mr = 66,052, containing 602 amino acid residues, is predicted. In composition the FrdA protein strongly resembles the flavoprotein subunits of two succinate dehydrogenases. Moreover, a sequence of nine consecutive residues is common to the flavoprotein subunits from fumarate reductase and the beef heart succinate dehydrogenase. This sequence contains a histidyl residue which probably services as the site for attachment of the FAD cofactor to the reductase.