Intestinal-type alkaline phosphatase
Details
- Name
- Intestinal-type alkaline phosphatase
- Synonyms
- 3.1.3.1
- IAP
- Gene Name
- ALPI
- Organism
- Bovine
- Amino acid sequence
>lcl|BSEQ0015731|Intestinal-type alkaline phosphatase MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA SVNGVRKRKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD HTKDPTLQEMTEVALRVVSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAGMFDNAIAKA NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL GGGSRPDVNDSTSEDPSYQQQAAVPQASETHGGEDVAVFARGPQAHLVHGVEEETFVAHI MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
- Number of residues
- 533
- Molecular Weight
- 57099.1
- Theoretical pI
- Not Available
- GO Classification
- Functionsalkaline phosphatase activity / magnesium ion binding / zinc ion bindingProcessesdephosphorylationComponentsanchored component of membrane / integral component of membrane / plasma membrane
- General Function
- Zinc ion binding
- Specific Function
- Not Available
- Pfam Domain Function
- Alk_phosphatase (PF00245)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell membrane
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P19111 UniProtKB Entry Name PPBI_BOVIN - General References
- Weissig H, Schildge A, Hoylaerts MF, Iqbal M, Millan JL: Cloning and expression of the bovine intestinal alkaline phosphatase gene: biochemical characterization of the recombinant enzyme. Biochem J. 1993 Mar 1;290 ( Pt 2):503-8. [Article]
- Culp JS, Hermodson M, Butler LG: The active-site and amino-terminal amino acid sequence of bovine intestinal alkaline phosphatase. Biochim Biophys Acta. 1985 Oct 18;831(3):330-4. [Article]
- Hua JC, Berger J, Pan YC, Hulmes JD, Udenfriend S: Partial sequencing of human adult, human fetal, and bovine intestinal alkaline phosphatases: comparison with the human placental and liver isozymes. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2368-72. [Article]
Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details