Meiotic recombination protein DMC1/LIM15 homolog
Details
- Name
- Meiotic recombination protein DMC1/LIM15 homolog
- Synonyms
- DMC1H
- LIM15
- Gene Name
- DMC1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009368|Meiotic recombination protein DMC1/LIM15 homolog MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR ISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE
- Number of residues
- 340
- Molecular Weight
- 37680.725
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / DNA binding / DNA-dependent ATPase activity / double-stranded DNA binding / four-way junction DNA binding / recombinase activity / single-stranded DNA bindingProcesseschromosome organization involved in meiotic cell cycle / DNA recombinase assembly / female gamete generation / male meiosis I / meiotic nuclear division / mitotic recombination / oocyte maturation / ovarian follicle development / reciprocal meiotic recombination / response to ionizing radiation / spermatid development / spermatogenesis / strand invasion / synapsisComponentschromosome / chromosome, telomeric region / condensed nuclear chromosome / nucleoplasm / nucleus
- General Function
- Single-stranded dna binding
- Specific Function
- May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
- Pfam Domain Function
- Rad51 (PF08423)
- Transmembrane Regions
- Not Available
- Cellular Location
- Nucleus
- Gene sequence
>lcl|BSEQ0013115|Meiotic recombination protein DMC1/LIM15 homolog (DMC1) ATGAAGGAGGATCAAGTTGTGGCGGAAGAACCAGGATTCCAAGATGAAGAGGAATCTTTG TTTCAAGATATTGACCTGTTACAGAAACATGGAATTAACGTGGCTGACATTAAGAAACTG AAATCAGTAGGAATCTGTACCATCAAAGGTATACAGATGACAACAAGAAGAGCTCTATGC AATGTCAAAGGACTCTCAGAAGCCAAAGTAGACAAGATTAAAGAGGCAGCGAACAAACTA ATTGAACCAGGATTCTTGACTGCATTTGAGTATAGTGAAAAGAGGAAAATGGTTTTCCAT ATCACCACCGGGAGCCAGGAATTTGATAAGTTACTAGGAGGTGGAATTGAAAGTATGGCA ATTACAGAAGCTTTTGGAGAATTTCGTACTGGAAAAACCCAGCTTTCTCATACCCTCTGT GGTGAACATCAGATGGAGCTACTTGATTATGTAGCAGCAAAGTTCCATGAAGAAGCTGGC ATCTTCAAGCTATTGATTATCGATTCAATAATGGCACTTTTTCGAGTGGATTTCAGTGGC CGTGGGGAGTTGGCCGAACGGCAGCAAAAATTGGCCCAGATGTTGTCACGACTCCAAAAA ATCTCAGAAGAATATAACGTGGCTGTTTTTGTGACCAATCAAATGACTGCCGATCCAGGA GCAACTATGACCTTTCAGGCAGATCCCAAAAAACCCATTGGGGGACACATTCTGGCTCAT GCTTCAACAACAAGAATAAGCTTGCGAAAGGGAAGAGGAGAGCTCAGAATTGCCAAGATT TATGACAGTCCTGAGATGCCTGAAAATGAAGCCACCTTCGCAATAACTGCTGGAGGAATT GGGGATGCCAAGGAGTAG
- Chromosome Location
- 22
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q14565 UniProtKB Entry Name DMC1_HUMAN HGNC ID HGNC:2927 - General References
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