| DB00185 | Cevimeline | A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome. |
| DB01019 | Bethanechol | A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. |
| DB01122 | Ambenonium | A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. |
| DB01400 | Neostigmine | A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. |
| DB01057 | Echothiophate | An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma. |
| DB13262 | Aceclidine | Aceclidine has been marketed in Europe but has not been used clinically in the United States. It is used in the treatment of open-angle glaucoma and is a parasympathomimetic agent. |
| DB00382 | Tacrine | For the palliative treatment of mild to moderate dementia of the Alzheimer's type. |
| DB00674 | Galantamine | A benzazepine derivative used to treat mild to moderate dementia associated with Alzheimer's Disease. |
| DB06709 | Methacholine | A parasympathomimetic bronchoconstrictor used during the bronchial challenge test for the diagnosis of bronchial hyperreactivity in subjects who do not have clinically apparent asthma. |
| DB00411 | Carbamoylcholine | A direct acting miotic agent administered ophthalmically to decrease intraocular pressure in glaucoma or after eye surgery, and to induce miosis during surgery. |
| DB00545 | Pyridostigmine | A cholinesterase inhibitor used to treat myasthenia gravis. |
| DB00944 | Demecarium | For the topical treatment of chronic open-angle glaucoma. |
| DB01085 | Pilocarpine | A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. |
| DB03128 | Acetylcholine | A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. |
| DB04660 | Choline alfoscerate | A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes... |
| DB13495 | Paraoxon | Not Annotated |
| DB13694 | Distigmine | Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase... |
| DB00981 | Physostigmine | A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. |
| DB15357 | Xanomeline | Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium). |