Arabinonucleosides

Name
Arabinonucleosides
Accession Number
DBCAT000481
Description

Nucleosides containing arabinose as their sugar moiety.

Drugs
DrugDrug Description
VidarabineAn antiviral agent used to treat various viral infections.
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
ElacytarabineInvestigated for use/treatment in leukemia (unspecified) and melanoma.
ClevudineInvestigated for use/treatment in hepatitis (viral, B).
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
SorivudineSorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
NetivudineNetivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
FiacitabineFiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
2'-fluoro-5-ethylarabinosyluracil2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma,...
FialuridineFialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
Drugs & Drug Targets
DrugTargetType
VidarabineDNA polymerase catalytic subunittarget
VidarabineThymidine kinasetarget
VidarabineThymidine kinasetarget
VidarabineAdenosine deaminaseenzyme
CytarabineDNA polymerase betatarget
CytarabineCytidine deaminaseenzyme
CytarabineSolute carrier family 22 member 4transporter
CytarabineMultidrug resistance-associated protein 7transporter
CytarabineEquilibrative nucleoside transporter 1transporter
CytarabineDNAtarget
CytarabineCytochrome P450 3A4enzyme
CytarabineDeoxycytidine kinaseenzyme
Cytarabine5'-nucleotidaseenzyme
CytarabineDeoxycytidylate deaminaseenzyme
FludarabineDNA polymerase alpha catalytic subunittarget
FludarabineRibonucleoside-diphosphate reductase large subunittarget
FludarabineEquilibrative nucleoside transporter 1transporter
FludarabineDNAtarget
FludarabineDeoxycytidine kinasetarget
FludarabineSolute carrier family 28 member 3transporter
ElacytarabineDeoxycytidine kinasetarget
ClofarabineDNA polymerase alpha catalytic subunittarget
ClofarabineRibonucleoside-diphosphate reductase large subunittarget
ClofarabineDeoxycytidine kinaseenzyme
ClofarabineDNAtarget
ClofarabineATP-binding cassette sub-family G member 2transporter