Name
Acridines
Accession Number
DBCAT000656
Description

Compounds that include the structure of acridine.

Drugs
DrugDrug Description
AmsacrineA cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
ProflavineA topical antiseptic agent used in wound dressings to prevent infections.
AminacrineA highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH...
EuflavineNot Annotated
Quinacrine mustardNot Available
Drugs & Drug Targets
DrugTargetType
AmsacrineDNA topoisomerase 2-alphatarget
AmsacrineDNAtarget
AmsacrinePotassium voltage-gated channel subfamily H member 2target
AmsacrineP-glycoprotein 1transporter
AmsacrineAlpha-1-acid glycoprotein 1target
AmsacrineSerum albumintarget
TacrineAcetylcholinesterasetarget
TacrineCytochrome P450 1A2enzyme
TacrineCholinesterasetarget
TacrineP-glycoprotein 1transporter
TacrineLiver carboxylesterase 1target
QuinacrineDNAtarget
Quinacrine85/88 kDa calcium-independent phospholipase A2target
QuinacrineCytosolic phospholipase A2target
QuinacrineInactive phospholipase C-like protein 1target
QuinacrineHistamine N-methyltransferaseenzyme
QuinacrineSolute carrier family 22 member 2transporter
QuinacrineP-glycoprotein 1transporter
QuinacrineCytochrome P450 3A4enzyme
QuinacrineCytochrome P450 3A5enzyme
ProflavineDNAtarget
ProflavineProthrombintarget
ProflavineHTH-type transcriptional regulator QacRtarget
ProflavineTetR family transcriptional repressor LfrRtarget
Quinacrine mustardTrypanothione reductasetarget