Digitalis Glycosides

Name
Digitalis Glycosides
Accession Number
DBCAT000820
Description

Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.

ATC Classification
Drugs
DrugDrug Description
DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
AcetyldigitoxinUsed for fast digitalization in congestive heart failure.
DeslanosideFor the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
MetildigoxinNot Annotated
Lanatoside CNot Annotated
GitoformateNot Annotated
AcetyldigoxinNot Annotated
DigoxigeninDigoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.
DigitoxigeninDigitoxigenin is a cardenolide which is the aglycon of digitoxin.
Drugs & Drug Targets
DrugTargetType
DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigoxinP-glycoprotein 1transporter
DigoxinSolute carrier organic anion transporter family member 4C1transporter
DigoxinBile salt export pumptransporter
DigoxinSolute carrier organic anion transporter family member 1A2transporter
DigoxinOrganic solute transporter subunit alphatransporter
DigoxinOrganic solute transporter subunit betatransporter
DigoxinSolute carrier organic anion transporter family member 1B1transporter
AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DeslanosideSodium/potassium-transporting ATPase subunit alpha-1target
DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigitoxinSerum albumincarrier
DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigitoxinCytochrome P450 3A4enzyme
DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DigitoxinP-glycoprotein 1transporter