Mineralocorticoid Receptor Antagonists
- Mineralocorticoid Receptor Antagonists
- Accession Number
Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE.
- ATC Classification
Drug Drug Description Spironolactone An aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Canrenoic acid Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Canrenone Canrenone has been used in trials studying the diagnostic of Heart Failure. Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
- Drugs & Drug Targets