- Accession Number
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Drug Drug Description Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Didanosine A reverse transcriptase inhibitor used to treat HIV. Zalcitabine A dideoxynucleoside used to treat HIV. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Fozivudine Tidoxil Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Racivir Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine DB00879 and its positive enantiomer. Racivir... Zidovudine monophosphate Not Available Zidovudine diphosphate Not Available
- Drugs & Drug Targets