Adrenergic alpha-2 Receptor Antagonists

Adrenergic alpha-2 Receptor Antagonists
Accession Number

Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS.

DrugDrug Description
AtipamezoleFor the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.
ORM-12741ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
IdazoxanIdazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
LurasidoneAn atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
EsmirtazapineInvestigated for use/treatment in insomnia and sleep disorders.
Drugs & Drug Targets
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
LurasidoneCytochrome P450 3A4enzyme
LurasidoneDopamine D2 receptortarget
Lurasidone5-hydroxytryptamine receptor 2Atarget
Lurasidone5-hydroxytryptamine receptor 7target
Lurasidone5-hydroxytryptamine receptor 1Atarget
LurasidoneAlpha-2C adrenergic receptortarget
LurasidoneAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Atarget
Mirtazapine5HT3 serotonin receptortarget
MirtazapineAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Ctarget
MirtazapineKappa-type opioid receptortarget
MirtazapineHistamine H1 receptortarget
MirtazapineCytochrome P450 1A2enzyme
MirtazapineCytochrome P450 3A4enzyme
MirtazapineCytochrome P450 2D6enzyme
MirtazapineAlpha-1 adrenergic receptorstarget
MirtazapineSodium-dependent serotonin transportertransporter
EsmirtazapineCytochrome P450 2D6enzyme
EsmirtazapineHistamine H1 receptortarget
Esmirtazapine5-hydroxytryptamine receptor 2target
EsmirtazapineAlpha-2 adrenergic receptorstarget