Cyclopropanes

Name
Cyclopropanes
Accession Number
DBCAT001393
Description

Three-carbon cycloparaffin cyclopropane (the structural formula (CH2)3) and its derivatives.

Drugs
DrugDrug Description
CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
MilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
LevomilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD).
Drugs & Drug Targets
DrugTargetType
CilastatinDipeptidase 1target
CilastatinSolute carrier family 22 member 6transporter
CilastatinSolute carrier family 22 member 8transporter
MilnacipranSodium-dependent serotonin transportertarget
MilnacipranSodium-dependent noradrenaline transportertarget
MilnacipranNMDA receptortarget
MilnacipranCytochrome P450 3A4enzyme
LevomilnacipranCytochrome P450 3A4enzyme
LevomilnacipranCytochrome P450 2C8enzyme
LevomilnacipranCytochrome P450 2C19enzyme
LevomilnacipranCytochrome P450 2D6enzyme
LevomilnacipranCytochrome P450 2J2enzyme
LevomilnacipranSodium-dependent serotonin transportertarget
LevomilnacipranSodium-dependent noradrenaline transportertarget
LevomilnacipranP-glycoprotein 1transporter