Collagen Type XVIII

All categories
Name
Collagen Type XVIII
Accession Number
DBCAT001799
Description

A non-fibrillar collagen found in BASEMENT MEMBRANE. The C-terminal end of the alpha1 chain of collagen type XVIII contains the ENDOSTATIN peptide, which can be released by proteolytic cleavage.

Drugs
DrugDrug Description
EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Drugs & Drug Targets
DrugTargetType
Endostatin72 kDa type IV collagenasetarget
EndostatinMatrix metalloproteinase-9target
EndostatinCollagenase 3target
EndostatinFocal adhesion kinase 1target
EndostatinE-selectintarget
EndostatinCytochrome P450 19A1enzyme