Pregnadien Derivatives

Pregnadien Derivatives
Accession Number
Not Available
ATC Classification
DrugDrug Description
MedrogestoneA progestin used as an adjunct to control secondary amenorrhea and dysfunctional bleeding in adolescent and adult females, and treat endometrial shedding in menopausal women.
NomegestrolNomegestrol is an ingredient in the EMA-authorised product Zoely.
PromegestoneNot Annotated
DemegestoneDemegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Megestrol acetateA progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
DydrogesteroneUsed to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history...
DienogestAn oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
ChlormadinoneNot Annotated
Drugs & Drug Targets
MedrogestoneSerum albumincarrier
MedrogestoneProgesterone receptortarget
MedrogestoneSex hormone-binding globulincarrier
MedrogestoneCorticosteroid-binding globulincarrier
MedrogestoneCytochrome P450 3A4enzyme
NomegestrolCytochrome P450 3A4enzyme
PromegestoneCytochrome P450 3A4enzyme
DemegestoneProgesterone receptortarget
DemegestoneCytochrome P450 3A4enzyme
Megestrol acetateProgesterone receptortarget
Megestrol acetateGlucocorticoid receptortarget
Megestrol acetateP-glycoprotein 1transporter
Megestrol acetateCytochrome P450 3A4enzyme
DydrogesteroneProgesterone receptortarget
DydrogesteroneCytochrome P450 3A4enzyme
DienogestCytochrome P450 3A4enzyme
DienogestProgesterone receptortarget
DienogestAndrogen receptortarget
ChlormadinoneCytochrome P450 3A4enzyme