Antigonadotropins and Similar Agents

Name
Antigonadotropins and Similar Agents
Accession Number
DBCAT002530
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
DanazolA synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts.
GestrinoneEndometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].
ElagolixA gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.
Drugs & Drug Targets
DrugTargetType
DanazolEstrogen receptor alphatarget
DanazolGonadotropin-releasing hormone receptortarget
DanazolPutative gonadotropin-releasing hormone II receptortarget
DanazolSex hormone-binding globulincarrier
DanazolC-C motif chemokine 2target
DanazolCytochrome P450 19A1enzyme
DanazolAndrogen receptortarget
DanazolProgesterone receptortarget
DanazolCytochrome P450 3A4enzyme
GestrinoneSex hormone-binding globulintarget
GestrinoneProgesterone receptortarget
GestrinoneGlucocorticoid receptortarget
GestrinoneAndrogen receptortarget
GestrinoneGonadotropin-releasing hormone receptortarget
GestrinoneEstrogen receptor alphatarget
GestrinoneCytochrome P450 3A4enzyme
ElagolixGonadotropin-releasing hormone receptortarget
ElagolixCytochrome P450 3A Subfamilyenzyme
ElagolixCytochrome P450 2D6enzyme
ElagolixCytochrome P450 2C8enzyme
ElagolixP-glycoprotein 1transporter
ElagolixSolute carrier organic anion transporter family member 1B1transporter